Cloning and sequence of the gene encoding a novel cefetoxime-hydrolyzing β-lactamase (CTX-M-9) from Escherichia coli in Spain

被引：110
作者：
Sabaté, M
Tarragó, F
Navarro, F
Miró, E
Vergés, C
Barbé, J
Prats, G
机构：
[1] Hosp Santa Cruz & San Pablo, Dept Microbiol, E-08025 Barcelona, Spain
[2] Univ Autonoma Barcelona, Dept Genet & Microbiol, Bellaterra 08193, Spain
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 07期
关键词：
D O I：
10.1128/AAC.44.7.1970-1973.2000
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A new CTX-M-type beta-lactamase (CTX-M-9) has been cloned from a clinical cefotaxime-resistant Escherichia coli strain. Despite the close identity that exists between the CTX-M-9 and Toho-2 beta-lactamases (88%), the 35 amino acids located between residues Ala-185 and Ala-219 are totally different in both enzymes. Outside of this region there are only six amino acids substitutions between both proteins.
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页码：1970 / 1973
页数：4
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