Chloride anion transport and copper-mediated DNA cleavage by C-ring functionalized prodigiosenes

被引:46
作者
Diaz, Rosa I. Saez
Regourd, Jasmine
Santacroce, Paul V.
Davis, Jeffery T.
Jakeman, David L.
Thompson, Alison [1 ]
机构
[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4J3, Canada
[2] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA
[3] Dalhousie Univ, Coll Pharm, Halifax, NS B3H 3J5, Canada
关键词
D O I
10.1039/b701919j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new class of prodigiosenes with stability-enhancing functionalities appended to the C-ring were found to transport chloride anions through liposomal membranes, as well as to induce copper-mediated DNA cleavage.
引用
收藏
页码:2701 / 2703
页数:3
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