Simple glucose sensors with micromolar sensitivity based on organic electrochemical transistors

被引：125
作者：
Macaya, Daniel J.
Nikolou, Maria
Takamatsu, Seiichi
Mabeck, Jeffrey T.
Owens, Roisin M.
Malliaras, George G. [1 ]
机构：
[1] Cornell Univ, Dept Mat Sci & Engn, Ithaca, NY 14853 USA
[2] Agave BioSyst, Ithaca, NY 14850 USA
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2007年 / 123卷 / 01期
基金：
美国国家科学基金会;
关键词：
organic semiconductors; biosensors; electrochemical transistors;
D O I：
10.1016/j.snb.2006.08.038
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple glucose biosensor with micromolar sensitivity is reported. The sensor utilizes a conducting polymer transistor, with a channel made out of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) and a Pt gate electrode. Glucose oxidase is used to confer specificity. It is shown that the sensor's response to glucose is well within the clinical range of glucose levels in human saliva. The sensitivity and range of detection of the sensor can be tuned by adjusting the magnitude of the gate bias. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：374 / 378
页数：5
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