Sesquiterpene coumarins from Ferula foetida

被引:19
作者
Abd El-Razek, Mohamed H.
Wu, Yang-Chang [1 ]
Chang, Fang-Rong
机构
[1] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung 807, Taiwan
[2] Natl Res Ctr, Chem Nat Cpds Dept, Cairo 12622, Cairo, Egypt
关键词
Ferula foetida; Umbelliferae; resin; sesquiterpene coumarin; CD;
D O I
10.1002/jccs.200700035
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A thorough investigation of the ethyl acetate soluble fraction from a methanol extract of the resin of Ferula foetida has resulted in the isolation of a new sesquiterpene coumarin namely epi-conferdione (1), along with four known compounds, colladonin (2), karatavicinol (3), 8-acetoxy-5-hydroxyumbelliprenin (4), and asacoumarin (5). These structures were elucidated on the basis of extensive spectroscopic techniques, including 1D and 2D NMR spectroscopy. The absolute configuration of the new compound was established by circular dichroism (CD).
引用
收藏
页码:235 / 238
页数:4
相关论文
共 16 条
[1]  
Abd El-Razek MH, 2004, HETEROCYCLES, V63, P2101
[2]  
Abd El-Razek MH, 2003, HETEROCYCLES, V60, P689
[3]  
Abd El-Razek MH, 2001, PHYTOCHEMISTRY, V57, P1201
[4]  
Ahmed AA, 1996, J NAT PROD, V59, P1171
[5]   An eudesmanolide and a carotane from Ferula sinaica [J].
Ahmed, AA ;
Abdel-Razek, MH ;
Nassar, MI ;
Izumi, S ;
Ohta, S ;
Hirata, T .
PHYTOCHEMISTRY, 2001, 57 (04) :513-515
[6]   Sesquiterpene coumarins and sesquiterpenes from Ferula sinaica [J].
Ahmed, AA .
PHYTOCHEMISTRY, 1999, 50 (01) :109-112
[7]  
APPENDINO G, 1994, PHYTOCHEMISTRY, V35, P183, DOI 10.1016/S0031-9422(00)90530-2
[8]   ASSAFOETIDIN AND FEROCOLICIN, 2 SESQUITERPENOID COUMARINS FROM FERULA-ASSAFOETIDA REGEL [J].
BANERJI, A ;
MALLICK, B ;
CHATTERJEE, A ;
BUDZIKIEWICZ, H ;
BREUER, M .
TETRAHEDRON LETTERS, 1988, 29 (13) :1557-1560
[9]   FOETIDIN, A SESQUITERPENOID COUMARIN FROM FERULA-ASSA-FOETIDA [J].
BUDDRUS, J ;
BAUER, H ;
ABUMUSTAFA, E ;
KHATTAB, A ;
MISHAAL, S ;
ELKHRISY, EAM ;
LINSCHEID, M .
PHYTOCHEMISTRY, 1985, 24 (04) :869-870
[10]  
DAWIDAR AA, 1979, CHEM PHARM BULL, V27, P3153