One-pot synthesis of 1,2-disubstituted pyrrolo[2,3-b]quinoxalines via palladium-catalyzed heteroannulation in water

被引：38

作者：

Keivanloo, Ali ^{[1
]}

Bakherad, Mohammad ^{[1
]}

Rahimi, Amin ^{[1
]}

Taheri, Sayed Ali Naghi ^{[1
]}

机构：

[1] Shahrood Univ Technol, Sch Chem, Shahrood, Iran

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 18期

关键词：

Palladium; Pyrroloquinoxaline; Alkyne; Sonogashira reaction; SONOGASHIRA COUPLING REACTION; 5-HT3 RECEPTOR AGONISTS; ARYL CHLORIDES; AQUEOUS-MEDIA; DERIVATIVES; HETEROCYCLIZATION; CHEMISTRY; ANALOGS; ALKYNES; DESIGN;

D O I：

10.1016/j.tetlet.2010.02.123

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of N-alkyl-3-chloroquinoxaline-2-amines with 1-alkynes, catalyzed by Pd-Cu, in the presence of sodium lauryl sulfate as the surfactant in water, leads to the one-pot formation of 1,2-disubstituted pyrrolo[2,3-b]quinoxalines in good-to-high yields. (C) 2010 Elsevier Ltd. All rights reserved.

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页码：2409 / 2412

页数：4

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