Design, synthesis and insecticidal activity of biphenyl-diamide derivatives

被引：13

作者：

Liu, Ye ^{[1
]}

Lei, Chao ^{[1
]}

Xu, Xiao-Yong ^{[1
]}

Shao, Xu-Sheng ^{[1
]}

Li, Zhong ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2016年 / 27卷 / 03期

关键词：

Diamide; Insecticide; Ryanodine insecticide; Biphenyl; ACID; FLUBENDIAMIDE; MODE;

D O I：

10.1016/j.cclet.2015.12.011

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diamides acting on insect ryanodine receptors are an intensive research area now. In order to search for novel candidates, a series of diamides containing biphenyl substructure were designed and synthesized. Their insecticidal activities against armyworms (Mythimna sepatara) and aphis (Aphis craccivora) were screened. The compounds with 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl substituent were found to be insecticidal to armyworms with the similar symptoms to poisoning by flubendiamide. In this research, we presented a novel type of diamide insecticide as a lead compound for further optimization. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：321 / 324

页数：4

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