Neoplasia of the tongue in a patient with Crohn's disease treated with azathioprine: case report

被引:12
作者
Li, ACY
Warnakulasuriya, S
Thompson, RPH
机构
[1] St Thomas Hosp, Rayne Inst, Gastrointestinal Lab, London SE1 7EH, England
[2] Guys Kings & St Thomas Sch Med & Dent, Dept Oral Med & Pathol, WHO Collaborating Ctr Oral Canc & Precanc, Kings Coll Dent Inst, London, England
关键词
azathioprine; inflammatory bowel disease; oral cancer;
D O I
10.1097/00042737-200302000-00013
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Azathioprine is now widely used for the maintenance treatment of Crohn's disease, but there are concerns whether azathioprine could predispose to malignancy in patients with inflammatory bowel disease. We report here a case of a 39-year-old non-smoking male with Crohn's disease who had been treated for 3 years with azathioprine and developed a lingual ulcer. Biopsy revealed squamous cell carcinoma in situ, a tumour not previously associated with Crohn's disease.
引用
收藏
页码:185 / 187
页数:3
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