Synthesis and micellization behavior of chiral amphiphilic diblock copolymers bearing amino acid/dipeptide pendants

被引：1

作者：

Hu, Zhiguo ^{[1
]}

Guo, Suzhen ^{[1
]}

Huang, Caihong ^{[1
]}

机构：

[1] Henan Normal Univ, Coll Chem & Environm Sci, Xinxiang 453007, Peoples R China

来源：

REACTIVE & FUNCTIONAL POLYMERS | 2010年 / 70卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Chiral; Amphiphilic; Block copolymer; Micelle; Click" chemistry; BLOCK-COPOLYMERS; MICELLES; POLYMERS; POLYMERIZATION; SURFACTANTS; MONOMERS; POLYACETYLENES; NANOPARTICLES; OXIDE); ACIDS;

D O I：

10.1016/j.reactfunctpolym.2009.12.001

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Novel chiral amphiphilic diblock copolymers bearing L-phenylalanine or alpha-L-aspartyl-L-phenylalanine methyl ester pendants were synthesized using a "click" reaction. The structure and composition of copolymers were characterized by gel permeation chromatography, (1)H NMR, elemental analysis and optical rotation measurements, which showed that the synthetic route can produce copolymers with well-defined composition and optical activity. The results from surface tension measurements, dynamic light scattering, transmission electron microscopy and (1)H NMR spectra indicated that these chiral copolymers formed spherical micelles with an optically active hydrophobic core in a NaH(2)PO(4) buffer (pH 4.5) system. (c) 2009 Elsevier Ltd. All rights reserved.

引用

页码：210 / 216

页数：7

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