Short report:: Variation in the 56-kD type-specific antigen gene of Orientia tsutsugamushi isolated from patients in Thailand

被引:14
作者
Kollars, TM [1 ]
Bodhidatta, D
Phulsuksombati, D
Tippayachai, B
Coleman, RE
机构
[1] USA, Ctr Hlth Promot & Prevent Med, Entomol Sci Program, Aberdeen Proving Ground, MD USA
[2] Armed Forces Res Inst Med Sci, Royal Thai Army Component, Div Res, Dept Biochem, Bangkok, Thailand
[3] Armed Forces Res Inst Med Sci, Royal Thai Army Component, Div Res, Dept Pathol, Bangkok, Thailand
[4] USA, Med Component, Dept Entomol, Armed Forces Res Inst Med Sci, Bangkok, Thailand
关键词
D O I
10.4269/ajtmh.2003.68.299
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The sequences of a 300-base pair region of the 56-kD type-specific antigen gene from 12 Orientia tsutsugamushi isolates from Thailand were compared with isolates from other regions in Asia. A high degree of heterogeneity was found among the 12 Thai isolates, with the C3 strain most commonly found. The abundance of the C3 strain of O. tsutsugamushi is of particular concern because doxycycline and chloramphenicol resistance have previously been reported in this strain.
引用
收藏
页码:299 / 300
页数:2
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