Genetics of heart development

被引：56

作者：

Chen, JN ^{[1
]}

Fishman, MC

机构：

[1] Univ Calif Los Angeles, Dept Mol Cell & Dev Biol, Los Angeles, CA 90095 USA

[2] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Charlestown, MA 02129 USA

[3] Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA

来源：

TRENDS IN GENETICS | 2000年 / 16卷 / 09期

关键词：

D O I：

10.1016/S0168-9525(00)02075-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genes that drive heart-cell differentiation in vertebrates and Drosophila are similar, even though the Drosophila 'heart' is a simple tube and the vertebrate heart is a multichambered physiologically complex organ. Mutational analysis in mice and, as particular focus of this review, in zebrafish, reveals the additional genes brought into play to fashion these evolutionarily 'new' organotypic components.

引用

页码：383 / 388

页数：6

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