Influence of the male on embryo quality

Early pregnancy failure or loss (EPL) represents a major source of wastage and inefficiency in livestock production systems. Although successful embryo development is dependent upon genetic and epigenetic contributions from both the male and female, potential adverse male affects on embryo quality and development are probably often underestimated. Of adverse male effects which have been identified, those associated with sperm and semen "quality" have been best characterized. In turn, although many factors can adversely impact semen quality, the mechanisms involved are relatively few. This presents opportunities for identifying biological markers for spermatogenic damage, as well as protective measures. Crown Copyright (c) 2007 Published by Elsevier Inc. All fights reserved.