Cardiac myosin-binding protein C in the heart

被引:0
|
作者
Carrier, Lucie
机构
[1] Univ Hamburg, Med Ctr, Inst Expt & Clin Pharmacol & Toxicol, D-20246 Hamburg, Germany
[2] INSERM, Inst Myol, U582, F-75013 Paris, France
[3] Univ Paris 06, UMR S582, IFR 14, F-75013 Paris, France
来源
ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX | 2007年 / 100卷 / 03期
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Understanding the structural and functional role of cardiac myosin-binding protein C in the heart is clinically relevant, as cMyBP-C gene mutations are a widely recognized cause of familial hypertrophic cardiomyopathy. Our knowledge about this protein considerably improved over the past decade. This review outlines several studies, which highlight the role of cardiac myosin-binding protein C and its phosphorylation in the heart in health and disease.
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页码:238 / 243
页数:6
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