A Novel Biginelli-Like Reaction: An Efficient One-pot Synthesis of Spiro[oxindole-quinazoline/pyrimidine]ones

被引：21
作者：
Kefayati, Hassan [1 ]
Rad-Moghadam, Kurosh [2 ]
Zamani, Masoumeh [1 ]
Hosseyni, Sanaz [1 ]
机构：
[1] Islamic Azad Univ, Dept Chem, Rasht Branch, Tehran, Iran
[2] Univ Guilan, Fac Sci, Dept Chem, Rasht, Iran
来源：
LETTERS IN ORGANIC CHEMISTRY | 2010年 / 7卷 / 04期
关键词：
Quinazolinone; pyrimidinone; spiro oxindole; multi-component reaction; Biginelli-like reaction; isatin; 3-COMPONENT CYCLOCONDENSATION REACTION; CONVENIENT SYNTHESIS; IMPROVED PROTOCOL; DIHYDROPYRIMIDINONES; CHLORIDE; ACID; UREA; CHEMISTRY; THIOUREAS; CATALYSIS;
D O I：
10.2174/157017810791130577
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Some new spiro[oxindole-quinazoline/pyrimidine]ones were synthesized via a novel three-component Biginelli-like reaction between isatin, cyclic or acyclic 1,3-dicarbonyl compounds, and urea, N-methyl urea or thiourea in one pot and good yields.
引用
收藏
页码：277 / 282
页数：6
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