Brucellosis presenting as myelofibrosis: First case report

被引：4

作者：

Bakri, Faris G. ^{[1
]}

Al-Bsoul, Nazzal M. ^{[2
]}

Magableh, Ahmad Y. ^{[2
]}

Shehabi, Asem ^{[3
]}

Tarawneh, Musleh ^{[4
]}

Al-Hadidy, Azmy M. ^{[5
]}

Abu-Fara, Mohammed A. ^{[1
]}

Awidi, Abdallah S. ^{[2
]}

机构：

[1] Jordan Univ Hosp, Div Infect Dis, Dept Med, Amman 11942, Jordan

[2] Jordan Univ Hosp, Div Hematol & Oncol, Dept Med, Amman 11942, Jordan

[3] Jordan Univ Hosp, Dept Pathol Microbiol, Amman 11942, Jordan

[4] Jordan Univ Hosp, Dept Pathol, Amman 11942, Jordan

[5] Jordan Univ Hosp, Dept Radiol, Amman 11942, Jordan

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2010年 / 14卷 / 02期

关键词：

Brucella; Pancytopenia; Myelofibrosis; Bone marrow; HEMATOLOGICAL MANIFESTATIONS; PANCYTOPENIA; INFECTION; CHILDREN;

D O I：

10.1016/j.ijid.2009.03.018

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We describe the case of a 29-year-old woman who presented with pancytopenia and myelofibrosis. Brucella melitensis was identified in her blood. The patient recovered completely with doxycycline and rifampin. A repeat bone marrow biopsy showed hypercellularity without myelofibrosis. Bone marrow findings in cases of pancytopenia due to brucellosis reveal normo-cellularity, hypercellularity, hemophagocytosis, or granuloma. To our knowledge this is the first report of brucellosis causing myelofibrosis. Brucellosis should be considered as a possible cause of myelofibrosis in endemic areas. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

引用

页码：E158 / E160

页数：3

共 23 条

[1]

Akbulut H, 2007, Indian J Med Microbiol, V25, P387

[2]

Akdeniz H, 1998, ACTA MED OKAYAMA, V52, P63

[3] Brucella bacteremia in patients with acute leukemia: A case series [J].

Al-Anazi K.A. ;

Al-Jasser A.M. .

Journal of Medical Case Reports, 1 (1)

[4]

ALEISSA YA, 1993, ACTA HAEMATOL-BASEL, V89, P132

[5] Brucella glomerulonephritis resulting in end-stage renal disease: a case report and a brief review of the literature [J].

Bakri, Faris G. ;

Wahbeh, Ayman ;

Mahafzah, Azmi ;

Tarawneh, Musleh .

INTERNATIONAL UROLOGY AND NEPHROLOGY, 2008, 40 (02) :529-533

[6] Brucellosis and hepatocellular carcinoma: Just a coincidence? [J].

Barutca, S ;

Sivri, B .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 1998, 93 (05) :854-855

[7] Complications associated with Brucella melitensis infection: A study of 530 cases [J].

Colmenero, JD ;

Reguera, JM ;

Martos, F ;

SanchezdeMora, D ;

Delgado, M ;

Causse, M ;

MartinFarfan, A ;

Juarez, C .

MEDICINE, 1996, 75 (04) :195-211

[8] HEMATOLOGIC CHANGES IN BRUCELLOSIS [J].

CROSBY, E ;

LLOSA, L ;

QUESADA, MM ;

CARRILLO, C ;

GOTUZZO, E .

JOURNAL OF INFECTIOUS DISEASES, 1984, 150 (03) :419-424

[9]

Garcia P, 1990, Enferm Infecc Microbiol Clin, V8, P19

[10]

HOFFMAN R, 2005, HEMATOLOGY BASIC PRI, P1255

← 1 2 3 →