Seroprevalence of IgG antibodies to hepatitis E in urban and rural southern India

被引：17

作者：

Vivek, Rosario ^{[1
]}

Chandy, George M. ^{[1
]}

Brown, David W. ^{[2
]}

Kang, Gagandeep ^{[1
]}

机构：

[1] Christian Med Coll & Hosp, Dept Gastrointestinal Sci, Vellore 632004, Tamil Nadu, India

[2] Hlth Protect Agcy, Ctr Infect, Virus Reference Dept, London NW9 5HT, England

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2010年 / 104卷 / 04期

关键词：

Hepatitis E virus; IgG antibodies; Seroprevalence; Rural populations; Urban populations; India; E VIRUS; PREVALENCE; INFECTION; DISEASE;

D O I：

10.1016/j.trstmh.2009.07.017

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Hepatitis E virus (HEV) is an important cause of sporadic and epidemic hepatitis E infection in northern India. Sera, collected from different age groups in rural (n = 1144) and urban (n = 1135) areas using a probability proportional to size survey, were tested using an ELISA for IgG antibodies. Antibodies increased with age in both populations, but the urban population had higher exposure in all age groups (Mann-Whitney U test, P<0.001 for all age groups except children <5 years). These results indicate that urban populations with higher density and common water supplies may be at greater risk of hepatitis E. (C) 2009 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

引用

页码：307 / 308

页数：2

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