A Precisely Defined Role for the Tip Link-Associated Protein TMIE in the Mechanoelectrical Transduction Channel Complex of Inner Ear Hair Cells

被引：3
作者：
Liedtke, Wolfgang [1 ,2 ,3 ,4 ,5 ,6 ]
机构：
[1] Duke Univ, Clin Pain Care, Dept Neurol, Durham, NC 27710 USA
[2] Duke Univ, Clin Pain Care, Dept Neurobiol, Durham, NC 27710 USA
[3] Duke Univ, Clin Pain Care, Dept Anesthesiol, Durham, NC 27710 USA
[4] Duke Univ, Clin Palliat Care, Dept Neurol, Durham, NC 27710 USA
[5] Duke Univ, Clin Palliat Care, Dept Neurobiol, Durham, NC 27710 USA
[6] Duke Univ, Clin Palliat Care, Dept Anesthesiol, Durham, NC 27710 USA
来源：
NEURON | 2014年 / 84卷 / 05期
关键词：
STEM-CELLS; HEARING; GENE; ZEBRAFISH; DFNB6;
D O I：
10.1016/j.neuron.2014.11.015
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：889 / 891
页数：3
相关论文
共 10 条
[1]   The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish [J].
Gleason, Michelle R. ;
Nagiel, Aaron ;
Jamet, Sophie ;
Vologodskaia, Maria ;
Lopez-Schier, Hernan ;
Hudspeth, A. J. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (50) :21347-21352
[2]   Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy [J].
Martell, Jeffrey D. ;
Deerinck, Thomas J. ;
Sancak, Yasemin ;
Poulos, Thomas L. ;
Mootha, Vamsi K. ;
Sosinsky, Gina E. ;
Ellisman, Mark H. ;
Ting, Alice Y. .
NATURE BIOTECHNOLOGY, 2012, 30 (11) :1143-+
[3]   Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6 [J].
Mitchem, KL ;
Hibbard, E ;
Beyer, LA ;
Bosom, K ;
Dootz, GA ;
Dolan, DF ;
Johnson, KR ;
Raphael, Y ;
Kohrman, DC .
HUMAN MOLECULAR GENETICS, 2002, 11 (16) :1887-1898
[4]   Mutations in a novel gene, TMIE, are associated with hearing loss linked to the DFNB6 locus [J].
Naz, S ;
Giguere, CM ;
Kohrman, DC ;
Mitchem, KL ;
Riazuddin, S ;
Morell, RJ ;
Ramesh, A ;
Srisailpathy, S ;
Deshmukh, D ;
Riazuddin, S ;
Griffith, AJ ;
Friedman, TB ;
Smith, RJH ;
Wilcox, ER .
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (03) :632-636
[5]   Mechanosensitive Hair Cell-like Cells from Embryonic and Induced Pluripotent Stem Cells [J].
Oshima, Kazuo ;
Shin, Kunyoo ;
Diensthuber, Marc ;
Peng, Anthony W. ;
Ricci, Anthony J. ;
Heller, Stefan .
CELL, 2010, 141 (04) :704-716
[6]   The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells [J].
Pepermans, Elise ;
Michel, Vincent ;
Goodyear, Richard ;
Bonnet, Crystel ;
Abdi, Samia ;
Dupont, Typhaine ;
Gherbi, Souad ;
Holder, Muriel ;
Makrelouf, Mohamed ;
Hardelin, Jean-Pierre ;
Marlin, Sandrine ;
Zenati, Akila ;
Richardson, Guy ;
Avan, Paul ;
Bahloul, Amel ;
Petit, Christine .
EMBO MOLECULAR MEDICINE, 2014, 6 (07) :984-992
[7]   Inner Ear Hair Cell-Like Cells from Human Embryonic Stem Cells [J].
Ronaghi, Mohammad ;
Nasr, Marjan ;
Ealy, Megan ;
Durruthy-Durruthy, Robert ;
Waldhaus, Joerg ;
Diaz, Giovanni H. ;
Joubert, Lydia-Marie ;
Oshima, Kazuo ;
Heller, Stefan .
STEM CELLS AND DEVELOPMENT, 2014, 23 (11) :1275-1284
[8]   The transmembrane inner ear (tmie) gene contributes to vestibular and lateral line development and function in the zebrafish (Danio rerio) [J].
Shen, Yu-Chi ;
Jeyabalan, Anandhi K. ;
Wu, Karen L. ;
Hunker, Kristina L. ;
Kohrman, David C. ;
Thompson, Deborah L. ;
Liu, Dong ;
Barald, Kate F. .
DEVELOPMENTAL DYNAMICS, 2008, 237 (04) :941-952
[9]   Preparation of cells and tissues for immuno EM [J].
Webster, Paul ;
Schwarz, Heinz ;
Griffiths, Gareth .
INTRODUCTION TO ELECTRON MICROSCOPY FOR BIOLOGISTS, 2008, 88 :45-58
[10]   TMIE Is an Essential Component of the Mechanotransduction Machinery of Cochlear Hair Cells [J].
Zhao, Bo ;
Wu, Zizhen ;
Grillet, Nicolas ;
Yan, Linxuan ;
Xiong, Wei ;
Harkins-Perry, Sarah ;
Mueller, Ulrich .
NEURON, 2014, 84 (05) :954-967
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