A diffusion and T2 relaxation MRI study of the ovine lumbar intervertebral disc under compression in vitro

被引:21
作者
Drew, SC [1 ]
Silva, P
Crozier, S
Pearcy, MJ
机构
[1] Univ Queensland, Ctr Magnet Resonance, Brisbane, Qld 4072, Australia
[2] Univ Queensland, Sch Informat Technol & Elect Engn, Brisbane, Qld 4072, Australia
[3] Queensland Univ Technol, Sch Mech Mfg & Med Engn, Brisbane, Qld 4001, Australia
关键词
D O I
10.1088/0031-9155/49/16/006
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The ovine lumbar intervertebral disc is a useful model for the human lumbar disc. We present preliminary estimates of diffusion coefficients and T-2 relaxation times in a pilot MRI study of the ovine lumbar intervertebral disc during uniaxial compression in vitro, and identify factors that hamper the ability to accurately monitor the temporal evolution of the effective diffusion tensor at high spatial resolution.
引用
收藏
页码:3585 / 3592
页数:8
相关论文
共 28 条
[1]   RECENT ADVANCES IN LUMBAR SPINAL MECHANICS AND THEIR CLINICAL-SIGNIFICANCE [J].
ADAMS, MA ;
DOLAN, P .
CLINICAL BIOMECHANICS, 1995, 10 (01) :3-19
[2]   Diffusion-weighted imaging of the spinal cord: Interleaved echo-planar imaging is superior to fast spin-echo [J].
Bammer, R ;
Augustin, M ;
Prokesch, RW ;
Stollberger, R ;
Fazekas, F .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2002, 15 (04) :364-373
[3]  
Basser PJ, 1996, J MAGN RESON SER B, V111, P209, DOI [10.1006/jmrb.1996.0086, 10.1016/j.jmr.2011.09.022]
[4]   ESTIMATION OF THE EFFECTIVE SELF-DIFFUSION TENSOR FROM THE NMR SPIN-ECHO [J].
BASSER, PJ ;
MATTIELLO, J ;
LEBIHAN, D .
JOURNAL OF MAGNETIC RESONANCE SERIES B, 1994, 103 (03) :247-254
[5]  
Basser PJ, 2000, MAGNET RESON MED, V44, P41, DOI 10.1002/1522-2594(200007)44:1<41::AID-MRM8>3.0.CO
[6]  
2-O
[7]  
BEARD HK, 1980, LUMBAR SPINE BACK PA, P407
[8]   COMPRESSIVE MECHANICAL-PROPERTIES OF THE HUMAN ANULUS FIBROSUS AND THEIR RELATIONSHIP TO BIOCHEMICAL-COMPOSITION [J].
BEST, BA ;
GUILAK, F ;
SETTON, LA ;
ZHU, WB ;
SAEDNEJAD, F ;
RATCLIFFE, A ;
WEIDENBAUM, M ;
MOW, VC .
SPINE, 1994, 19 (02) :212-221
[9]  
Chiu E J, 2001, Spine (Phila Pa 1976), V26, pE437, DOI 10.1097/00007632-200110010-00017
[10]  
CHIU EJ, 1997, P 43 ANN M ORTH RES