Merits and caveats of propensity scores to adjust for confounding

被引:56
作者
Fu, Edouard L. [1 ]
Groenwold, Rolf H. H. [1 ]
Zoccali, Carmine [2 ]
Jager, Kitty J. [3 ]
van Diepen, Merel [1 ]
Dekker, Friedo W. [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands
[2] CNR, IFC, Ctr Clin Physiol Clin Epidemiol Renal Dis & Hyper, Reggio Di Calabria, Italy
[3] Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Amsterdam UMC, Dept Med Informat,ERA EDTA Registry, Meibergdreef 9, Amsterdam, Netherlands
关键词
cohort studies; confounding; dialysis; observational research; propensity score; SELECTION; BIAS; SUBCLASSIFICATION; KNOWLEDGE; DIALYSIS;
D O I
10.1093/ndt/gfy283
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Proper adjustment for confounding is essential when estimating the effects of treatments or risk factors on health outcomes in observational data. To this end, various statistical methods have been developed. In the past couple of years, the use of propensity scores (PSs) to control for confounding has increased. Proper understanding of this method is necessary to critically appraise research in which it is applied. In this article, we provide an overview of PS methods, explaining their concept, advantages and possible disadvantages. Furthermore, the use of PS matching, PS adjustment and PS weighting is illustrated using data from the Netherlands Cooperative Study on the Adequacy of Dialysis (NECOSAD) cohort of dialysis patients.
引用
收藏
页码:1629 / 1635
页数:7
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