Application of glycosylation in targeted drug delivery

被引：56

作者：

Chen, Fang ^{[1
]}

Huang, Gangliang ^{[1
]}

机构：

[1] Chongqing Normal Univ, Act Carbohydrate Res Inst, Chongqing Key Lab Inorgan Funct Mat, Chongqing 401331, Peoples R China

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2019年 / 182卷

关键词：

Glycosylation; Targeted drug delivery; Mechanisms; Application; CONJUGATED CHITOSAN NANOPARTICLES; SOLID LIPID NANOPARTICLES; IN-VIVO; PHOTODYNAMIC THERAPY; LECTIN RECEPTORS; DENDRITIC CELLS; HEPATOCELLULAR-CARCINOMA; MANNOSYLATED LIPOSOMES; LOADED NANOPARTICLES; ENDOTHELIAL RECEPTOR;

D O I：

10.1016/j.ejmech.2019.111612

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Sugar, as a carrier of human energy and an important bioinformatics molecule, plays a vital role in many important physiological processes, and can control the transmission of bioinformatics by specific recognition with biological molecules such as proteins. Herein, the mechanism of glycosylation-targeted drug delivery was described, various glycosylation methods were summarized, and the applications of glycosylation-targeted drug delivery in liver targeting, brain targeting and lung targeting were discussed. At the same time, the problems of glycosylation targeted drug delivery were suggested, and the application prospects of glycosylation targeting drug delivery were expected. (C) 2019 Elsevier Masson SAS. All rights reserved.

引用

页数：10

共 139 条

[1]

Ahmed M, 2015, NANOMEDICINE-UK, V10, P2263, DOI [10.2217/NNM.15.58, 10.2217/nnm.15.58]

[2] Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine [J].

Andey, Terrick ;

Patel, Apurva ;

Marepally, Srujan ;

Chougule, Mahavir ;

Spencer, Shawn D. ;

Rishi, Arun K. ;

Singh, Mandip .

PLOS ONE, 2016, 11 (01)

[3] 18F-Fluorodeoxyglucamines: Reductive amination of hydrophilic 18F-fluoro-2-deoxyglucose with lipophilic amines for the development of potential PET imaging agents [J].

Baranwal, Aparna ;

Mukherjee, Jogeshwar .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 25 (15) :2902-2906

[4] Activation of innate host defense mechanisms by Borrelia [J].

Berende, Anneleen ;

Oosting, Marije ;

Kullberg, Bart-Jan ;

Netea, Mihai G. ;

Joosten, Leo A. B. .

EUROPEAN CYTOKINE NETWORK, 2010, 21 (01) :7-18

[5] Lactosylated Glycogen Nanoparticles for Targeting Prostate Cancer Cells [J].

Besford, Quinn A. ;

Wojnilowicz, Marcin ;

Suma, Tomoya ;

Bertleff-Zieschang, Nadja ;

Caruso, Frank ;

Cayalieri, Francesca .

ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (20) :16870-16880

[6] A 3D model for the human hepatic asialoglycoprotein receptor (ASGP-R) [J].

Bianucci, AM ;

Chiellini, F .

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2000, 18 (03) :435-451

[7] Glycoconjugated Site-Selective DNA-Methylating Agent Targeting Glucose Transporters on Glioma Cells [J].

Buchanan, Mairin K. ;

Needham, Chase N. ;

Neill, Nina E. ;

White, Maria C. ;

Kelly, Charles B. ;

Mastro-Kishton, Kelly ;

Chauvigne-Hines, Lacie M. ;

Goodwin, Tyler J. ;

McIver, Andrew L. ;

Bartolotti, Libero J. ;

Frampton, Arthur R. ;

Bourdelais, Andrea J. ;

Varadarajan, Sridhar .

BIOCHEMISTRY, 2017, 56 (02) :421-440

[8] Conjugation of Bovine Serum Albumin and Glucose under Combined High Pressure and Heat [J].

Buckow, Roman ;

Wendorff, Johannes ;

Hemar, Yacine .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 59 (08) :3915-3923

[9] Doxorubicin-loaded nanoparticles consisted of cationic- and mannose-modified-albumins for dual-targeting in brain tumors [J].

Byeon, Hyeong Jun ;

Thao, Le Quang ;

Lee, Seunghyun ;

Min, Sun Young ;

Lee, Eun Seong ;

Shin, Beom Soo ;

Choi, Han-Gon ;

Youn, Yu Seok .

JOURNAL OF CONTROLLED RELEASE, 2016, 225 :301-313

[10] Targeted photodynamic therapy of breast cancer cells using lactose-phthalocyanine functionalized gold nanoparticles [J].

Calavia, Paula Garcia ;

Chambrier, Isabelle ;

Cook, Michael J. ;

Haines, Alan H. ;

Field, Robert A. ;

Russell, David A. .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2018, 512 :249-259

← 1 2 3 4 5 6 7 8 9 10 →