Safety and Durability of Ponatinib in Patients With Philadelphia Chromosome-Positive (Ph plus ) Leukemia: Long-term Follow-up of an Ongoing Phase 1 Study

被引:0
作者
Mauro, Michael J. [1 ]
Cortes, Jorge E. [2 ]
Kantarjian, Hagop M. [2 ]
Shah, Neil P. [3 ]
Bixby, Dale [4 ]
Flinn, Ian W. [5 ]
O'Hare, Thomas [6 ]
Hu, Simin [8 ]
Rivera, Victor M. [8 ]
Clackson, Tim [8 ]
Turner, Christopher D. [8 ]
Haluska, Frank G. [8 ]
Druker, Brian J. [7 ]
Deininger, Michael W. [6 ,7 ]
Talpaz, Moshe [4 ]
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA
[3] Univ Calif San Francisco, San Francisco, CA 94143 USA
[4] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA
[5] Sarah Cannon Res Inst, Nashville, TN USA
[6] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA
[7] Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA
[8] ARIAD Pharmaceut Inc, Cambridge, MA 02139 USA
关键词
D O I
10.1016/j.clml.2014.06.069
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
404
引用
收藏
页码:S137 / S138
页数:2
相关论文
共 50 条
  • [1] SAFETY AND DURABILITY OF PONATINIB IN PATIENTS WITH PHILADELPHIA CHROMOSOME-POSITIVE (PH plus ) LEUKEMIA: LONG-TERM FOLLOW-UP OF AN ONGOING PHASE 1 STUDY
    Mauro, M.
    Cortes, J.
    Kantarjian, H.
    Shah, N.
    Bixby, D.
    Flinn, I.
    O'Hare, T.
    Hu, S.
    Rivera, V.
    Clackson, T.
    Turner, C.
    Haluska, F.
    Druker, B.
    Deininger, Mi
    Talpaz, M.
    HAEMATOLOGICA, 2013, 98 : 295 - 296
  • [2] Safety and durability of ponatinib in patients with Philadelphia chromosome-positive (Ph plus ) leukemia: Long-term follow-up of an ongoing phase I study
    Mauro, Michael J.
    Cortes, Jorge E.
    Kantarjian, Hagop M.
    Shah, Neil P.
    Bixby, Dale
    Flinn, Ian
    O'Hare, Thomas
    Hu, Simin
    Rivera, Victor M.
    Clackson, Tim
    Turner, Christopher D.
    Haluska, Frank G.
    Druker, Brian J.
    Deininger, Michael W. N.
    Talpaz, Moshe
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [3] LONGER-TERM FOLLOW-UP OF A PHASE 1 STUDY OF PONATINIB IN PATIENTS (PTS) WITH PHILADELPHIA CHROMOSOME-POSITIVE (PH plus ) LEUKEMIAS
    Cortes, J.
    Talpaz, M.
    Kantarjian, H. M.
    Shah, N. P.
    Bixby, D.
    Flinn, I. W.
    O'Hare, T.
    Hu, S.
    Rivera, V.
    Clackson, T.
    Turner, C.
    Haluska, F.
    Druker, B. J.
    Deininger, M. W.
    Mauro, M. J.
    HAEMATOLOGICA, 2014, 99 : 335 - 335
  • [4] Long-Term Follow-up of the Efficacy and Safety of Ponatinib in Philadelphia Chromosome-Positive Leukemia Patients with the T315I Mutation
    Jabbour, Elias J.
    Cortes, Jorge E.
    Talpaz, Moshe
    Baccarani, Michele
    Mauro, Michael J.
    Hochhaus, Andreas
    Hughes, Timothy P.
    Guilhot, Francois
    Deininger, Michael W.
    Shah, Neil
    Bixby, Dale L.
    Flinn, Ian W.
    O'Hare, Thomas
    Lustgarten, Stephanie
    Rivera, Victor M.
    Santillana, Sergio
    Kantarjian, Hagop M.
    BLOOD, 2016, 128 (22)
  • [5] Longer-term follow up of a phase I study of ponatinib in patients (pts) with Philadelphia chromosome-positive (Ph plus ) leukemias.
    Talpaz, Moshe
    Cortes, Jorge E.
    Kantarjian, Hagop M.
    Shah, Neil P.
    Bixby, Dale L.
    Flinn, Ian
    O'Hare, Thomas
    Hu, Simin
    Rivera, Victor M.
    Clackson, Tim
    Turner, Christopher D.
    Haluska, Frank G.
    Drucker, Brian J.
    Deininger, Michael W. N.
    Mauro, Michael J.
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [6] Long-Term Anti-Leukemic Activity of Ponatinib in Patients with Philadelphia Chromosome-Positive Leukemia: Updated Results from an Ongoing Phase 1 Study
    Deininger, Michael W.
    Cortes, Jorge E.
    Kantarjian, Hagop M.
    Shah, Neil
    Bixby, Dale
    Mauro, Michael J.
    Flinn, Ian W.
    O'Hare, Thomas
    Hu, Simin
    Dorer, David J.
    Rivera, Victor M.
    Clackson, Tim
    Turner, Christopher D.
    Haluska, Frank G.
    Druker, Brian J.
    Talpaz, Moshe
    BLOOD, 2012, 120 (21)
  • [7] Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
    Ravandi, Farhad
    O'Brien, Susan M.
    Cortes, Jorge E.
    Thomas, Deborah M.
    Garris, Rebecca
    Faderl, Stefan
    Burger, Jan A.
    Rytting, Michael E.
    Ferrajoli, Alessandra
    Wierda, William G.
    Verstovsek, Srdan
    Champlin, Richard
    Kebriaei, Partow
    McCue, Deborah A.
    Huang, Xuelin
    Jabbour, Elias
    Garcia-Manero, Guillermo
    Estrov, Zeev
    Kantarjian, Hagop M.
    CANCER, 2015, 121 (23) : 4158 - 4164
  • [8] Ponatinib in Japanese patients with Philadelphia chromosome-positive leukemia, a phase 1/2 study
    Arinobu Tojo
    Taiichi Kyo
    Kazuhito Yamamoto
    Hirohisa Nakamae
    Naoto Takahashi
    Yukio Kobayashi
    Tetsuzo Tauchi
    Shinichiro Okamoto
    Koichi Miyamura
    Kiyohiko Hatake
    Hiromi Iwasaki
    Itaru Matsumura
    Noriko Usui
    Tomoki Naoe
    Meera Tugnait
    Narayana I. Narasimhan
    Stephanie Lustgarten
    Heinrich Farin
    Frank Haluska
    Kazuma Ohyashiki
    International Journal of Hematology, 2017, 106 : 385 - 397
  • [9] Ponatinib in Japanese patients with Philadelphia chromosome-positive leukemia, a phase 1/2 study
    Tojo, Arinobu
    Kyo, Taiichi
    Yamamoto, Kazuhito
    Nakamae, Hirohisa
    Takahashi, Naoto
    Kobayashi, Yukio
    Tauchi, Tetsuzo
    Okamoto, Shinichiro
    Miyamura, Koichi
    Hatake, Kiyohiko
    Iwasaki, Hiromi
    Matsumura, Itaru
    Usui, Noriko
    Naoe, Tomoki
    Tugnait, Meera
    Narasimhan, Narayana I.
    Lustgarten, Stephanie
    Farin, Heinrich
    Haluska, Frank
    Ohyashiki, Kazuma
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2017, 106 (03) : 385 - 397
  • [10] Long-term follow-up of imatinib plus combination chemotherapy in patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
    Lim, Sung-Nam
    Joo, Young-Don
    Lee, Kyoo-Hyung
    Kim, Dae-Young
    Lee, Je-Hwan
    Lee, Jung-Hee
    Chi, Hyun-Sook
    Yun, Sung-Cheol
    Lee, Won Sik
    Lee, Sang Min
    Park, Seonyang
    Kim, Inho
    Sohn, Sang Kyun
    Moon, Joon Ho
    Ryoo, Hun-Mo
    Bae, Sung Hwa
    Hyun, Myung Soo
    Kim, Min Kyoung
    Kim, Hyeoung Joon
    Yang, Deok-Hwan
    Eom, Hyeon-Seok
    Lee, Gyeong-Won
    Jung, Chul Won
    Won, Jong-Ho
    Kim, Hawk
    Lee, Jae-Hoon
    Shin, Ho-Jin
    Jang, Dae-Young
    AMERICAN JOURNAL OF HEMATOLOGY, 2015, 90 (11) : 1013 - 1020