The membrane protein universe: what's out there and why bother?

被引：169

作者：

von Heijne, G. ^{[1
]}

机构：

[1] Stockholm Univ, Ctr Biomembrane Res, Dept Biochem & Biophys, SE-10691 Stockholm, Sweden

来源：

JOURNAL OF INTERNAL MEDICINE | 2007年 / 261卷 / 06期

关键词：

membrane protein; GPCR; aquaporin; ion channel; transporter; ATP synthase;

D O I：

10.1111/j.1365-2796.2007.01792.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chances are that you have come across membrane proteins many times in your professional life: ion channels, aquaporins, G-protein-coupled receptors, drug resistance proteins. But it is also quite likely that you have never bothered to think about what the implications are of being a membrane protein, as opposed to a soluble protein. What is special about membrane proteins in terms of structure and function, how many membrane proteins are out there, how are they made in the cell? Welcome to the membrane protein universe!.

引用

页码：543 / 557

页数：15

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