Windows into development: historic, current, and future perspectives on transgenic zebrafish

被引：135
作者：
Udvadia, AJ [1 ]
Linney, E [1 ]
机构：
[1] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USA
来源：
DEVELOPMENTAL BIOLOGY | 2003年 / 256卷 / 01期
关键词：
zebrafish; transgenic; time-lapse; gene regulation;
D O I：
10.1016/S0012-1606(02)00083-0
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation and morphogenetic movements. The optical clarity and rapid early development of zebrafish provides the ability to follow these events as they occur in live, developing embryos. This article will review the development of transgenic technology in zebrafish as well as the current and future uses of transgenic zebrafish to explore the dynamic environment of the developing vertebrate embryo. (C) 2003 Elsevier Science (USA). All rights reserved.
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页码：1 / 17
页数：17
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