Frailty in Older Persons

被引：306
作者：
Cesar, Matteo [1 ]
Calvani, Riccardo [2 ]
Marzetti, Emanuele [2 ]
机构：
[1] Univ Toulouse III Paul Sabatier, Univ Hosp Toulouse, Gerontopole, 37 Allees Jules Guesde, F-31000 Toulouse, France
[2] Univ Cattolica Sacro Cuore, Ctr Med Invecchiamento, Largo Francesco Vito 1, I-00168 Rome, Italy
来源：
CLINICS IN GERIATRIC MEDICINE | 2017年 / 33卷 / 03期
关键词：
Pieability; Geriatrics; Assessment; Elderly; Prevention; LOWER-EXTREMITY FUNCTION; NURSING-HOME ADMISSION; ELDERLY-PEOPLE; RANDOMIZED-TRIAL; GAIT SPEED; CARE; DISABILITY; HEALTH; ADULTS; INDEX;
D O I：
10.1016/j.cger.2017.02.002
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Frailty is a clinical state characterized by a decrease of an individual's homeostatic reserves and is responsible for enhanced vulnerability to endogenous and/or exogenous stressors. Such a condition of extreme vulnerability exposes individuals to an increased risk of negative health related outcomes. Multiple operational definitions of frailty are available in the literature, but none can be indicated as a gold standard. Frailty should be considered a condition of major interest for public health and become the lever for reshaping the obsolete health care systems currently unable to adequately address the clinical needs of aging populations.
引用
收藏
页码：293 / +
页数：12
相关论文
共 61 条
  • [11] Fighting Against Age Discrimination in Clinical Trials
    Cherubini, Antonio
    Del Signore, Susanna
    Ouslander, Joe
    Semla, Todd
    Michel, Jean-Pierre
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2010, 58 (09) : 1791 - 1796
  • [12] Frailty in elderly people
    Clegg, Andrew
    Young, John
    Iliffe, Steve
    Rikkert, Marcel Olde
    Rockwood, Kenneth
    [J]. LANCET, 2013, 381 (9868) : 752 - 762
  • [13] Frailty and resilience from physics to medicine
    Conti, Andrea A.
    Conti, Antonio
    [J]. MEDICAL HYPOTHESES, 2010, 74 (06) : 1090 - 1090
  • [14] Frailty: an emerging concept for general practice
    De Lepeleire, Jan
    Iliffe, Steve
    Mann, Eva
    Degryse, Jean Marie
    [J]. BRITISH JOURNAL OF GENERAL PRACTICE, 2009, 59 (562) : 364 - 369
  • [15] Comprehensive geriatric assessment for older adults admitted to hospital
    Ellis, Graham
    Whitehead, Martin A.
    O'Neill, Desmond
    Langhorne, Peter
    Robinson, David
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2011, (07):
  • [16] Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women
    Ensrud, Kristine E.
    Ewing, Susan K.
    Taylor, Brent C.
    Fink, Howard A.
    Cawthon, Peggy M.
    Stone, Katie L.
    Hillier, Teresa A.
    Cauley, Jane A.
    Hochberg, Marc C.
    Rodondi, Nicolas
    Tracy, J. Kathleen
    Cummings, Steven R.
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2008, 168 (04) : 382 - 389
  • [17] Reliability of a Frailty Index Based on the Clinical Assessment of Health Deficits in Male C57BL/6J Mice
    Feridooni, Hirad A.
    Sun, Michael H.
    Rockwood, Kenneth
    Howlett, Susan E.
    [J]. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2015, 70 (06): : 686 - 693
  • [18] Frailty in older adults: Evidence for a phenotype
    Fried, LP
    Tangen, CM
    Walston, J
    Newman, AB
    Hirsch, C
    Gottdiener, J
    Seeman, T
    Tracy, R
    Kop, WJ
    Burke, G
    McBurnie, MA
    [J]. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2001, 56 (03): : M146 - M156
  • [19] Fried LP, 2004, J GERONTOL A-BIOL, V59, P255
  • [20] Testing an integral conceptual model of frailty
    Gobbens, Robbert J.
    van Assen, Marcel A.
    Luijkx, Katrien G.
    Schols, Jos M.
    [J]. JOURNAL OF ADVANCED NURSING, 2012, 68 (09) : 2047 - 2060
1234567