Synthesis of Hyperbranched β-Galceramide-Containing Dendritic Polymers that Bind HIV-1 rgp120

被引:11
作者
Antonio Morales-Serna, Jose [1 ]
Boutureira, Omar [1 ]
Serra, Angels [1 ]
Isabel Matheu, M. [1 ]
Diaz, Yolanda [1 ]
Castillon, Sergio [1 ]
机构
[1] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43007, Spain
关键词
Polymers; Hyperbranched polymers; Glycolipids; Glycoconjugates; Dendrimers; Galceramide; HIV; GLYCODENDRITIC STRUCTURES; QUANTITATIVE MEASUREMENTS; IMMUNODEFICIENCY-VIRUS; CLICK CHEMISTRY; LIPID RAFTS; DENDRIMERS; GALACTOSYLCERAMIDE; GLYCOSPHINGOLIPIDS; MULTIVALENT; SPHINGOSINE;
D O I
10.1002/ejoc.201000132
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report the design, synthesis, and characterization of a series of water-soluble hyperbranched beta-galceramide-containing dendritic. Polymers showing useful binding ability to HIV-1 rgp120 as demonstrated with surface plasmon resonance.
引用
收藏
页码:2657 / 2660
页数:4
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