Synthesis of Hyperbranched β-Galceramide-Containing Dendritic Polymers that Bind HIV-1 rgp120

被引：11

作者：

Antonio Morales-Serna, Jose ^{[1
]}

Boutureira, Omar ^{[1
]}

Serra, Angels ^{[1
]}

Isabel Matheu, M. ^{[1
]}

Diaz, Yolanda ^{[1
]}

Castillon, Sergio ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43007, Spain

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 2010卷 / 14期

关键词：

Polymers; Hyperbranched polymers; Glycolipids; Glycoconjugates; Dendrimers; Galceramide; HIV; GLYCODENDRITIC STRUCTURES; QUANTITATIVE MEASUREMENTS; IMMUNODEFICIENCY-VIRUS; CLICK CHEMISTRY; LIPID RAFTS; DENDRIMERS; GALACTOSYLCERAMIDE; GLYCOSPHINGOLIPIDS; MULTIVALENT; SPHINGOSINE;

D O I：

10.1002/ejoc.201000132

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report the design, synthesis, and characterization of a series of water-soluble hyperbranched beta-galceramide-containing dendritic. Polymers showing useful binding ability to HIV-1 rgp120 as demonstrated with surface plasmon resonance.

引用

页码：2657 / 2660

页数：4

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