Microparticulate and nanotechnology mediated drug delivery system for the delivery of herbal extracts

被引:34
作者
Dubey, Sunil Kumar [1 ]
Parab, Shraddha [2 ]
Achalla, Vaishnav Pavan Kumarr [2 ]
Narwaria, Avinash [1 ]
Sharma, Swapnil [3 ]
Gowda, B. H. Jaswanth [4 ]
Kesharwani, Prashant [5 ,6 ]
机构
[1] Emami Ltd, R&D Healthcare Div, Kolkata, India
[2] Birla Inst Technol & Sci, Dept Pharm, Pilani, Rajasthan, India
[3] Banasthali Vidyapith, Dept Pharm, Banasthali, India
[4] Yenepoya Deemed Univ, Yenepoya Pharm Coll & Res Ctr, Dept Pharmaceut, Mangalore, India
[5] Jamia Hamdard, Dept Pharmaceut, Sch Pharmaceut Educ & Res, New Delhi 110062, India
[6] Chandigarh Univ, Univ Inst Pharma Sci, Mohali, India
关键词
Microspheres; phytoconstituents; herbal; novel drug delivery; microcapsules; BIODEGRADABLE POLYMERS; ENCAPSULATION; MICROENCAPSULATION; STABILITY; MICROSPHERES; ANTIOXIDANTS; MEDICINES;
D O I
10.1080/09205063.2022.2065408
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
There has been a growing interest in the scientific community to explore the complete potential of phytoconstituents, herbal or plant-based ingredients owing to a range of benefits they bring along. The herbal plants accommodate many phytoconstituents that are responsible for various activities such as anti-oxidant, antimicrobial, anticancer, anti-inflammatory, anti-allergic, hepatoprotective, etc. However, these phytoconstituents are highly sensitive to several environmental and physiological factors such as pH, oxygen, heat, temperature, humidity, stomach acid, enzymes, and light. Hence, there is need for the development of a drug delivery system that can protect the phytoconstituents from both internal and external conditions. In this regard, a microparticulate drug delivery system is considered amongst the ideal choice owing to its small size, ability to protect the environment-sensitive active constituents, in achieving sustained drug delivery, targeted drug delivery, protection of the drug from physiological conditions, minimizing drug-related side effects, etc.
引用
收藏
页码:1531 / 1554
页数:24
相关论文
共 96 条
[1]   Biomaterials in treatment of Alzheimer's disease [J].
Agrawal, Mukta ;
Prathyusha, Eluri ;
Ahmed, Hafiz ;
Dubey, Sunil Kumar ;
Kesharwani, Prashant ;
Singhvi, Gautam ;
Naidu, V. G. M. ;
Alexander, Amit .
NEUROCHEMISTRY INTERNATIONAL, 2021, 145
[2]   Stimuli-responsive In situ gelling system for nose-to-brain drug delivery [J].
Agrawal, Mukta ;
Saraf, Shailendra ;
Saraf, Swarnlata ;
Dubey, Sunil K. ;
Puri, Anu ;
Gupta, Umesh ;
Kesharwani, Prashant ;
Ravichandiran, V ;
Kumar, Pramod ;
Naidu, V. G. M. ;
Murty, Upadhyayula Suryanarayana ;
Ajazuddin ;
Alexander, Amit .
JOURNAL OF CONTROLLED RELEASE, 2020, 327 :235-265
[3]  
Ahirrao S.P., 2014, J PHARM NANOTECHNOL, V2, P1
[4]   Applications of novel drug delivery system for herbal formulations [J].
Ajazuddin ;
Saraf, S. .
FITOTERAPIA, 2010, 81 (07) :680-689
[5]   Biodegradable polymers as encapsulation materials for cosmetics and personal care markets [J].
Ammala, Anne .
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 2013, 35 (02) :113-124
[6]   Bioactive antimicrobial agents for finishing of textiles for health care products [J].
Babu, K. Murugesh ;
Ravindra, K. B. .
JOURNAL OF THE TEXTILE INSTITUTE, 2015, 106 (07) :706-717
[7]   Overview on Therapeutic Applications of Microparticulate Drug Delivery Systems [J].
Bale, Swarna ;
Khurana, Amit ;
Reddy, A. Shiva Shankar ;
Singh, Mandip ;
Godugu, Chandraiah .
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 2016, 33 (04) :309-361
[8]  
Bandawane A, 2019, Journal of Drug Delivery and Therapeutics, V9, P517, DOI [10.22270/jddt.v9i3.2610, DOI 10.22270/JDDT.V9I3.2610, 10.22270/jddt.v9i2.2407, DOI 10.22270/JDDT.V9I2.2407]
[9]  
Bayraktar O., 2019, DRUG DISCOVERY, V13, P39, DOI DOI 10.1016/J.CIS.2015.05.003
[10]   Protein-reinforced and chitosan-pectin coated alginate microparticles for delivery of flavan-3-ol antioxidants and caffeine from green tea extract [J].
Belscak-Cvitanovic, Ana ;
Dorcevic, Verica ;
Karlovic, Sven ;
Pavlovic, Vladimir ;
Komes, Drazenka ;
Jezek, Damir ;
Bugarski, Branko ;
Nedovic, Viktor .
FOOD HYDROCOLLOIDS, 2015, 51 :361-374