Gold catalyzed synthesis of fluorinated tetrahydrofurans and lactones

被引:11
作者
Malhotra, Deepika [1 ]
Liu, Leping [1 ]
Wang, Weibo [1 ]
Durham, Mallory [1 ]
Hammond, Gerald B. [1 ]
Xu, Bo [1 ]
机构
[1] Univ Louisville, Dept Chem, Louisville, KY 40292 USA
基金
美国国家科学基金会;
关键词
Gold catalysis; Fluorination; Selectfluor; AMINOFLUORINATION; SELECTFLUOR;
D O I
10.1016/j.jfluchem.2014.05.014
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The gold catalyzed tandem cycloisomerization/fluorination of alkynylic alcohols gives difluoro hydroxyl tetrahydrofurans at room temperature in moderate to good yields. The gold catalyzed monofluorolactonization of alkynylic acids to the corresponding fluoro lactones was also explored. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:179 / 183
页数:5
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