Controlled association of hydrophobized polysaccharide by cyclodextrin

被引：51

作者：

Akiyoshi, K ^{[1
]}

Sasaki, Y ^{[1
]}

Kuroda, K ^{[1
]}

Sunamoto, J ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Synthet Chem & Biol Chem, Sakyo Ku, Kyoto 60601, Japan

来源：

CHEMISTRY LETTERS | 1998年 / 01期

关键词：

D O I：

10.1246/cl.1998.93

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The self-aggregate of cholesterol-bearing pullulan (CHP) dissociated by complexation with beta-cyclodextrin (beta-CD) to yield a dis-aggregated CHP-CD complex, in which the cholesteryl group was a suitable guest to beta-CD. The monodisperse nanoparticles of the CHP self-aggregate were regenerated by addition of 1-adamantancarboxylic acid (ADC), which is the better guest molecule to beta-CD than cholesterol. CD regulated the association and dissociation of hydrophobized polysaccharides in water.

引用

页码：93 / 94

页数：2

共 11 条

[1] Microscopic structure and thermoresponsiveness of a hydrogel nanoparticle by self-assembly of a hydrophobized polysaccharide [J].

Akiyoshi, K ;

Deguchi, S ;

Tajima, H ;

Nishikawa, T ;

Sunamoto, J .

MACROMOLECULES, 1997, 30 (04) :857-861

[2] SELF-AGGREGATES OF HYDROPHOBIZED POLYSACCHARIDES IN WATER - FORMATION AND CHARACTERISTICS OF NANOPARTICLES [J].

AKIYOSHI, K ;

DEGUCHI, S ;

MORIGUCHI, N ;

YAMAGUCHI, S ;

SUNAMOTO, J .

MACROMOLECULES, 1993, 26 (12) :3062-3068

[3]

Akiyoshi K., 1996, SUPRAMOL SCI, V3, P157, DOI [10.1016/0968-5677(96)00031-4, DOI 10.1016/0968-5677(96)00031-4]

[4] Cholesterol recognition and binding by cyclodextrin dimers [J].

Breslow, R ;

Zhang, BL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (35) :8495-8496

[5]

GUSTAVO GG, 1997, LANGMUIR, V13, P2235

[6]

HARADA A, 1996, POLYM PREPRINTS JPN, V45, P2472

[7] Protein folding in the central cavity of the GroEL-GroES chaperonin complex [J].

Mayhew, M ;

daSilva, ACR ;

Martin, J ;

ErdjumentBromage, H ;

Tempst, P ;

Hartl, FU .

NATURE, 1996, 379 (6564) :420-426

[8]

MEIK W, 1996, MACROMOL RAPID COMM, V17, P731

[9] SUPRAMOLECULAR ASSEMBLY BETWEEN NANOPARTICLES OF HYDROPHOBIZED POLYSACCHARIDE AND SOLUBLE-PROTEIN COMPLEXATION BETWEEN THE SELF-AGGREGATE OF CHOLESTEROL-BEARING PULLULAN AND ALPHA-CHYMOTRYPSIN [J].

NISHIKAWA, T ;

AKIYOSHI, K ;

SUNAMOTO, J .

MACROMOLECULES, 1994, 27 (26) :7654-7659

[10] Macromolecular complexation between bovine serum albumin and the self-assembled hydrogel nanoparticle of hydrophobized polysaccharides [J].

Nishikawa, T ;

Akiyoshi, K ;

Sunamoto, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (26) :6110-6115

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