Ionic current model of rabbit retinal horizontal cell

被引：13

作者：

Aoyama, T

Kamiyama, Y

Usui, S ^{[1
]}

Blanco, R

Vaquero, CF

de la Villa, P

机构：

[1] Toyohashi Univ Technol, Dept Informat & Comp Sci, Aichi 4418580, Japan

[2] Aichi Prefectural Univ, Fac Informat Sci & Technol, Aichi 4801198, Japan

[3] Univ Alcala de Henares, Sch Med, Dept Physiol & Pharmacol, Madrid 28871, Spain

来源：

NEUROSCIENCE RESEARCH | 2000年 / 37卷 / 02期

关键词：

rabbit; retinal horizontal cell; ionic current model; simulation; repetitive; action potential;

D O I：

10.1016/S0168-0102(00)00111-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We propose a mathematical model of rabbit retinal horizontal cell based on the ionic current mechanisms. Five types of ionic currents in rabbit retinal horizontal cell, I-Na, I-Ca, I-Kv, I-A and I-Ka, are described by Hodgkin-Huxley type equations based on voltage clamp measurements. In simulation the model reproduced similar responses to voltage and current clamp experiments. Under the current clamp experiment a repetitive action potential was found on A-type rabbit horizontal cells. Our result suggests that the repetitive action potential is generated by an interaction Of I-Ca and I-Kv. (C) 2000 Elsevier Science Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

引用

页码：141 / 151

页数：11

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