Asthma and Allergic Inflammation

被引:329
作者
Locksley, Richard M. [1 ]
机构
[1] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA
基金
美国国家卫生研究院;
关键词
LUNG DENDRITIC CELLS; CLASS-II EXPRESSION; IMMUNE-RESPONSES; T-CELLS; IN-VIVO; AIRWAY; INNATE; IL-4; BASOPHILS; RECEPTOR;
D O I
10.1016/j.cell.2010.03.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of these chronic inflammatory disorders.
引用
收藏
页码:777 / 783
页数:7
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