Viability Assessment With Global Left Ventricular Longitudinal Strain Predicts Recovery of Left Ventricular Function After Acute Myocardial Infarction

被引:80
作者
Mollema, Sjoerd A. [1 ]
Delgado, Victoria [1 ]
Bertini, Matteo [1 ]
Antoni, M. Louisa [1 ]
Boersma, Eric [3 ]
Holman, Eduard R. [1 ]
Stokkel, Marcel P. M. [2 ]
van der Wall, Ernst E. [1 ]
Schalij, Martin J. [1 ]
Bax, Jeroen J. [1 ]
机构
[1] Leiden Univ, Dept Cardiol, Med Ctr, NL-2333 ZA Leiden, Netherlands
[2] Leiden Univ, Dept Nucl Med, Med Ctr, NL-2333 ZA Leiden, Netherlands
[3] Erasmus Univ, Dept Epidemiol & Biostat, Med Ctr, NL-3000 DR Rotterdam, Netherlands
关键词
echocardiography; myocardial contraction; myocardial infarction; ventricles; viability; SPECKLE TRACKING ECHOCARDIOGRAPHY; CORONARY ANGIOPLASTY; EJECTION FRACTION; PROGNOSTIC VALUE; DYSFUNCTION; SIZE; QUANTIFICATION; VALIDATION; HEART;
D O I
10.1161/CIRCIMAGING.108.802785
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-The extent of viable myocardial tissue is recognized as a major determinant of recovery of left ventricular (LV) function after myocardial infarction. In the current study, the role of global LV strain assessed with novel automated function imaging (AFI) to predict functional recovery after acute infarction was evaluated. Methods and Results-A total of 147 patients (mean age, 61 +/- 11 years) admitted for acute myocardial infarction were included. All patients underwent 2D echocardiography within 48 hours of admission. Significant relations were observed between baseline AFI global LV strain and peak level of troponin T (r=0.64), peak level of creatine phosphokinase (r=0.62), wall motion score index (r=0.52), and viability index assessed with single-photon emission computed tomography (r=0.79). At 1-year follow-up, LV ejection fraction was reassessed. Patients with absolute improvement in LV ejection fraction >= 5% at 1-year follow-up (n=70; 48%) had a higher (more negative) baseline AFI global LV strain (P<0.0001). Baseline AFI global LV strain was a predictor for change in LV ejection fraction at 1-year follow-up. A cutoff value for baseline AFI global LV strain of -13.7% yielded a sensitivity of 86% and a specificity of 74% to predict LV functional recovery at 1-year follow-up. Conclusions-AFI global LV strain early after acute myocardial infarction reflects myocardial viability and predicts recovery of LV function at 1-year follow-up. (Circ Cardiovasc Imaging. 2010;3:15-23.)
引用
收藏
页码:15 / 23
页数:9
相关论文
共 26 条
  • [1] Noninvasive myocardial strain measurement by speckle tracking echocardiography - Validation against sonomicrometry and tagged magnetic resonance imaging
    Amundsen, BH
    Helle-Valle, T
    Edvardsen, T
    Torp, H
    Crosby, J
    Lyseggen, E
    Stoylen, A
    Ihlen, H
    Lima, JAC
    Smiseth, OA
    Slordahl, SA
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (04) : 789 - 793
  • [2] Myocardial deformation imaging based on ultrasonic pixel tracking to identify reversible myocardial dysfunction
    Becker, Michael
    Lenzen, Alexandra
    Ocklenburg, Christina
    Stempel, Katharina
    Kuehl, Harald
    Neizel, Miria
    Katoh, Markus
    Kramann, Rafael
    Wildberger, Joachim
    Kelm, Malte
    HofFmann, Rainer
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (15) : 1473 - 1481
  • [3] Automated function imaging: a new operator-independent strain method for assessing left ventricular function
    Belghiti, H.
    Brette, S.
    Lafitte, S.
    Reant, P.
    Picard, F.
    Serri, K.
    Lafitte, M.
    Courregelongue, M.
    Dos Santos, P.
    Douard, H.
    Roudaut, R.
    DeMaria, A.
    [J]. ARCHIVES OF CARDIOVASCULAR DISEASES, 2008, 101 (03) : 163 - 169
  • [4] Bolognese L, 1997, CIRCULATION, V96, P3353
  • [5] Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart - A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association
    Cerqueira, MD
    Weissman, NJ
    Dilsizian, V
    Jacobs, AK
    Kaul, S
    Laskey, WK
    Pennell, DJ
    Rumberger, JA
    Ryan, T
    Verani, MS
    [J]. CIRCULATION, 2002, 105 (04) : 539 - 542
  • [6] Prognostic value of myocardial viability detected by myocardial contrast echocardiography early after acute myocardial infarction
    Dwivedi, Girish
    Janardhanan, Rajesh
    Hayat, Sajad A.
    Swinburn, John M.
    Senior, Roxy
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 50 (04) : 327 - 334
  • [7] PROGRESSIVE LEFT-VENTRICULAR DYSFUNCTION AND REMODELING AFTER MYOCARDIAL-INFARCTION - POTENTIAL MECHANISMS AND EARLY PREDICTORS
    GAUDRON, P
    EILLES, C
    KUGLER, I
    ERTL, G
    [J]. CIRCULATION, 1993, 87 (03) : 755 - 763
  • [8] GERMANO G, 1995, J NUCL MED, V36, P2138
  • [9] Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease
    Gjesdal, Ola
    Hopp, Einar
    Vartdal, Trond
    Lunde, Ketil
    Helle-Valle, Thomas
    Aakhus, Svend
    Smith, Hans-Jorgen
    Ihlen, Hallfdan
    Edvardsen, Thor
    [J]. CLINICAL SCIENCE, 2007, 113 (5-6) : 287 - 296
  • [10] Methods and limitations of assessing new noninvasive tests - Part II: Outcomes-based validation and reliability assessment of noninvasive testing
    Hachamovitch, Rory
    Di Carli, Marcelo F.
    [J]. CIRCULATION, 2008, 117 (21) : 2793 - 2801