In Vitro Enzyme Inhibitory Activity of Ten Ferulago W. Koch Species Growing in Turkey

被引：4
作者：
Akkol, Esra Kupeli [1 ]
Gunbatan, Tugba [1 ]
Gurbuz, Ilhan [1 ]
Duman, Hayri [2 ]
Kilic, Ceyda Sibel [3 ]
Ilhan, Mert [4 ]
机构：
[1] Gazi Univ, Fac Pharm, Dept Pharmacognosy, Ankara, Turkey
[2] Gazi Univ, Fac Sci, Dept Biol, Ankara, Turkey
[3] Ankara Univ, Fac Pharm, Dept Pharmaceut Bot, Ankara, Turkey
[4] Van Yuzuncu Yil Univ, Fac Pharm, Dept Pharmacognosy, Van, Turkey
来源：
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY | 2022年 / 65卷
关键词：
Ferulago; Collagenase; Elastase; Hyaluronidase; Wound; HUMAN NEUTROPHIL ELASTASE; ESSENTIAL OIL COMPOSITION; CHEMICAL-COMPOSITION; ANTIMICROBIAL ACTIVITIES; MEDICINAL-PLANTS; MATRIX METALLOPROTEINASES; ISAURICA PESMEN; SYRIACA BOISS; AERIAL PARTS; WOUND REPAIR;
D O I：
10.1590/1678-4324-2022210207
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Ferulago species are traditionally used for the treatment of skin diseases, bronchitis, and depression, to increase body strength, as an immunostimulant, aphrodisiac and sedative in Anatolia. In this study, hyaluronidase, collagenase and elastase inhibitory potential relevant to wound healing activities of ethanol extracts from the roots of ten Ferulago species [F. cassia Boiss., F. humilis Boiss., F. isaurica Pesmen, F. longistylis Boiss., F. mascrosciadia Boiss. & Balansa, F. sandrasica Pesmen & Quezel, F. setifolia K. Koch., F. silaifolia (Boiss.) Boiss., F. trojana Akalin & Pimenov formerly known as F. sylvatica (Besser) Rchb. and F. syriaca Boiss.] were investigated. Ethanol extracts of F. mascrosciadia and F. syriaca were the most active ones against collagenase and elastase, respectively. In vitro wound healing activity of ten Ferulago species is reported for the first time in the current study.
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页数：11
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