Translocation t(8;16)(p11;p13) in acute non-lymphocytic leukemia: Report on two new cases and review of the literature

被引：30

作者：

Velloso, ERP ^{[1
]}

Mecucci, C ^{[1
]}

Michaux, L ^{[1
]}

vanOrshoven, A ^{[1
]}

Stul, M ^{[1
]}

Boogaerts, M ^{[1
]}

Bosly, A ^{[1
]}

Cassiman, JJ ^{[1
]}

VandenBerghe, H ^{[1
]}

机构：

[1] CATHOLIC UNIV LEUVEN,CTR HUMAN GENET,B-3000 LOUVAIN,BELGIUM

来源：

LEUKEMIA & LYMPHOMA | 1996年 / 21卷 / 1-2期

关键词：

acute nonlymphocytic leukemia; immunophenotyping; translocation; cytogenetic analysis; prognosis;

D O I：

10.3109/10428199609067591

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two new cases of t(8;16)(p11;p13) in acute nonlymphocytic leukemia (ANLL) are described. These two patients in addition to the 34 previously described, showed a striking association with myelomonocytic (M4) or monocytic (M5) leukemia, extramedullary infiltration, erythrophagocytosis and disseminated intravascular coagulation. One of our patients showed a TCR beta gene rearrangement. Alltogether 36 cases of t(8;16) ANLL have been documented until today. We here review their clinical and cytogenetic features.

引用

页码：137 / 142

页数：6

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