Translocation t(8;16)(p11;p13) in acute non-lymphocytic leukemia: Report on two new cases and review of the literature

被引：30

作者：

Velloso, ERP ^{[1
]}

Mecucci, C ^{[1
]}

Michaux, L ^{[1
]}

vanOrshoven, A ^{[1
]}

Stul, M ^{[1
]}

Boogaerts, M ^{[1
]}

Bosly, A ^{[1
]}

Cassiman, JJ ^{[1
]}

VandenBerghe, H ^{[1
]}

机构：

[1] CATHOLIC UNIV LEUVEN,CTR HUMAN GENET,B-3000 LOUVAIN,BELGIUM

来源：

LEUKEMIA & LYMPHOMA | 1996年 / 21卷 / 1-2期

关键词：

acute nonlymphocytic leukemia; immunophenotyping; translocation; cytogenetic analysis; prognosis;

D O I：

10.3109/10428199609067591

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two new cases of t(8;16)(p11;p13) in acute nonlymphocytic leukemia (ANLL) are described. These two patients in addition to the 34 previously described, showed a striking association with myelomonocytic (M4) or monocytic (M5) leukemia, extramedullary infiltration, erythrophagocytosis and disseminated intravascular coagulation. One of our patients showed a TCR beta gene rearrangement. Alltogether 36 cases of t(8;16) ANLL have been documented until today. We here review their clinical and cytogenetic features.

引用

页码：137 / 142

页数：6

共 34 条

[1] TRANSLOCATION T(8-16)(P11-P13) IN ACUTE NONLYMPHOBLASTIC LEUKEMIA (M4) POSSIBLY SECONDARY TO HODGKINS-DISEASE [J].

BARBATA, G ;

CARBONE, P ;

MIRTO, S ;

SANTORO, A ;

GIGLIO, MC ;

GRANATA, G .

CANCER GENETICS AND CYTOGENETICS, 1989, 37 (01) :127-131

[2] TRANSLOCATION T(8-16) IN ACUTE MONOCYTIC LEUKEMIA [J].

BECHER, R ;

HAAS, OA ;

GRAEVEN, U ;

BETTELHEIM, P ;

AMBROS, P ;

FRIDRIK, M ;

SCHAEFER, UW ;

SCHMIDT, CG .

CANCER GENETICS AND CYTOGENETICS, 1988, 34 (02) :265-271

[3] A UNIQUE 8-16 TRANSLOCATION IN 2 INFANTS WITH POORLY DIFFERENTIATED MONOBLASTIC LEUKEMIA [J].

BERNSTEIN, R ;

PINTO, MR ;

SPECTOR, I ;

MACDOUGALL, LG .

CANCER GENETICS AND CYTOGENETICS, 1987, 24 (02) :213-220

[4] CHROMOSOME PATTERNS IN 26 SOUTH-AFRICAN CHILDREN WITH ACUTE NONLYMPHOCYTIC LEUKEMIA (ANLL) [J].

BERNSTEIN, R ;

MACDOUGALL, LG ;

PINTO, MR .

CANCER GENETICS AND CYTOGENETICS, 1984, 11 (02) :199-214

[5] A COMPLEX T(3-8-17) INVOLVING BREAKPOINT 8P11 IN A CASE OF M5 ACUTE NONLYMPHOCYTIC LEUKEMIA WITH ERYTHROPHAGOCYTOSIS [J].

BERTHEAS, MF ;

JAUBERT, J ;

VASSELON, C ;

REYNAUD, J ;

POMIER, G ;

LEPETIT, JC ;

HAGEMEIJER, A ;

BRIZARD, CP .

CANCER GENETICS AND CYTOGENETICS, 1989, 42 (01) :67-73

[6] THE 8P11 ANOMALY IN MONOBLASTIC LEUKEMIA [J].

BRIZARD, A ;

GUILHOT, F ;

HURET, JL ;

BENZLEMOINE, E ;

TANZER, J .

LEUKEMIA RESEARCH, 1988, 12 (08) :693-697

[7] TRANSLOCATION (8-16) IN ACUTE MYELOMONOCYTIC LEUKEMIA [J].

BROOKWELL, R ;

HUNT, FA .

CANCER GENETICS AND CYTOGENETICS, 1988, 32 (02) :297-298

[8] T-CELL RECEPTOR AND IMMUNOGLOBULIN GENE REARRANGEMENTS IN ACUTE MYELOBLASTIC-LEUKEMIA [J].

CHENG, GY ;

MINDEN, MD ;

TOYONAGA, B ;

MAK, TW ;

MCCULLOCH, EA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1986, 163 (02) :414-424

[9] TRANSLOCATION T(8-16)(P11-P13) IN NEONATAL ACUTE MONOCYTIC LEUKEMIA [J].

HANADA, T ;

ONO, I ;

MINOSAKI, Y ;

MORIYAMA, N ;

NAKAHARA, S ;

OHTSU, A .

EUROPEAN JOURNAL OF PEDIATRICS, 1991, 150 (05) :323-324

[10] THE TRANSLOCATION T(8 16)(P11 P13) DEFINES AN AML SUBTYPE WITH DISTINCT CYTOLOGY AND CLINICAL-FEATURES [J].

HANSLIP, JJ ;

SWANSBURY, GJ ;

PINKERTON, R ;

CATOVSKY, D .

LEUKEMIA & LYMPHOMA, 1992, 6 (06) :479-&

← 1 2 3 4 →