Saracatinib impairs maintenance of human T-ALL by targeting the LCK tyrosine kinase in cells displaying high level of lipid rafts

被引：9

作者：

Buffiere, Anne ^{[1
,2
]}

Accogli, Theo ^{[1
]}

Saint-Paul, Laetitia ^{[1
,2
]}

Lucchi, Geraldine ^{[3
]}

Uzan, Benjamin ^{[4
,5
]}

Ballerini, Paola ^{[6
]}

Bastie, Jean-Noel ^{[1
,2
,7
,8
]}

Delva, Laurent ^{[1
,2
]}

Pflumio, Francoise ^{[4
,5
]}

Quere, Ronan ^{[1
,2
]}

机构：

[1] Univ Bourgogne Franche Comte, INSERM, UMR1231, Dijon, France

[2] Labex LipSTIC, Dijon, France

[3] Univ Bourgogne Franche Comte, Plateforme Prote, Dijon, France

[4] Univ Paris 11, Univ Paris 07, CEA, UMR967,Inserm, Fontenay Aux Roses, France

[5] CEA, IRCM, LSHL, Fontenay Aux Roses, France

[6] Hop Trousseau, AP HP, Lab Hematol, Paris, France

[7] Hop Univ Francois Mitterrand, Serv Hematol Clin, Dijon, France

[8] Hop Univ Francois Mitterrand, CRB Ferdinand Cabanne, BB-0033-00044, Dijon, France

来源：

LEUKEMIA | 2018年 / 32卷 / 09期

关键词：

ACUTE LYMPHOBLASTIC-LEUKEMIA; MULTIPLE-MYELOMA; RECEPTOR; RECRUITMENT; EDELFOSINE; APOPTOSIS; PATHWAYS;

D O I：

10.1038/s41375-018-0081-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：2062 / 2065

页数：4

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