Novel environmentally benign procedure for the synthesis of 2-aryl- and 2-hetaryl-4(3H)-quinazolinones

被引：13
|
作者：
Deligeorgiev, T. G. [1 ]
St Kaloyanova [1 ]
Vasilev, A. [1 ]
Vaquero, J-J [2 ]
Alvarez-Builla, J. [2 ]
Cuadro, Ana M. [2 ]
机构：
[1] Univ Sofia, Fac Chem, Sofia 1164, Bulgaria
[2] Univ Alcala de Henares, Fac Pharm, Madrid 28871, Spain
来源：
COLORATION TECHNOLOGY | 2010年 / 126卷 / 01期
关键词：
ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; AGENTS;
D O I：
10.1111/j.1478-4408.2010.00223.x
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A novel environmentally benign procedure for the synthesis of 2-aryl- or 2-hetaryl-4(3H)-quinazolinones by condensation of anthranilamide with various aromatic aldehydes in polyethylene glycol under microwave irradiation has been developed. In contrast with other reported methods, this procedure provides the corresponding quinazolinones with good to high yields and purity, in very short reaction times and without the use of an oxidant.
引用
收藏
页码：24 / 30
页数：7
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