The use of bis(trimethylsilyl) acetamide and bis(trimethylsilyl) urea for protection and as control reagents in synthesis

被引：0

作者：

El Gihani, MT ^{[1
]}

Heaney, H ^{[1
]}

机构：

[1] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

来源：

SYNTHESIS-STUTTGART | 1998年 / 04期

关键词：

azetidinones; Friedel-Crafts reactions; Lewis acids; nitrogen heterocycles; palladium catalysis; phosphorus compounds; stereochemistry;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The oxophilicity of silicon allows the efficient protection of a range of hydroxyfunctionalities using either N,O-bis(trimethylsilyl)acetamide (BSA) or N,N-bis(trimethylsilyl)urea (BSU). Three distinct mechanistic pathways are proposed for the reactions of the reagents which explain the mild reaction conditions that can be used to achieve a number of important synthetic transformations. The reactions include examples where improved stereochemical control results from the use of BSA.

引用

页码：357 / 375

页数：19

共 13 条

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