Apaf-1/cytochrome capoptosome: an essential initiator of caspase activation or just a sideshow?

被引：86
作者：
Baliga, B [1 ]
Kumar, S [1 ]
机构：
[1] Hanson Inst, Adelaide, SA 5000, Australia
来源：
CELL DEATH AND DIFFERENTIATION | 2003年 / 10卷 / 01期
关键词：
D O I：
10.1038/sj.cdd.4401166
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
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页码：16 / 18
页数：3
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共 29 条
[1]   Defects in regulation of apoptosis in caspase-2-deficient mice [J].
Bergeron, L ;
Perez, GI ;
Macdonald, G ;
Shi, LF ;
Sun, Y ;
Jurisicova, A ;
Varmuza, S ;
Latham, KE ;
Flaws, JA ;
Salter, JCM ;
Hara, H ;
Moskowitz, MA ;
Li, E ;
Greenberg, A ;
Tilly, JL ;
Yuan, JY .
GENES & DEVELOPMENT, 1998, 12 (09) :1304-1314
[2]   Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions [J].
Butt, AJ ;
Harvey, NL ;
Parasivam, G ;
Kumar, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (12) :6763-6768
[3]   Ecdysone-induced expression of the caspase DRONC during hormone-dependent programmed cell death in Drosophila is regulated by Broad-Complex [J].
Cakouros, D ;
Daish, T ;
Martin, D ;
Baehrecke, EH ;
Kumar, S .
JOURNAL OF CELL BIOLOGY, 2002, 157 (06) :985-995
[4]   Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor - A novel function for a caspase prodomain [J].
Colussi, PA ;
Harvey, NL ;
Kumar, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (38) :24535-24542
[5]   Conversion of procaspase-3 to an autoactivating caspase by fusion to the caspase-2 prodomain [J].
Colussi, PA ;
Harvey, NL ;
Shearwin-Whyatt, LM ;
Kumar, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (41) :26566-26570
[6]   The role of cytochrome c in caspase activation in Drosophila melanogaster cells [J].
Dorstyn, L ;
Read, S ;
Cakouros, D ;
Huh, JR ;
Hay, BA ;
Kumar, S .
JOURNAL OF CELL BIOLOGY, 2002, 156 (06) :1089-1098
[7]   DRONC, an ecdysone-inducible Drosophila caspase [J].
Dorstyn, L ;
Colussi, PA ;
Quinn, LM ;
Richardson, H ;
Kumar, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (08) :4307-4312
[8]   The mitochondrion: Is it central to apoptosis? [J].
Finkel, E .
SCIENCE, 2001, 292 (5517) :624-626
[9]   Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria [J].
Guo, Y ;
Srinivasula, SM ;
Druilhe, A ;
Fernandes-Alnemri, T ;
Alnemri, ES .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (16) :13430-13437
[10]   Functional activation of Nedd2/ICH-1 (Caspase-2) is an early process in apoptosis [J].
Harvey, NL ;
Butt, AJ ;
Kumar, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (20) :13134-13139
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