4-HYDROXY-2-QUINOLONES. 169. SYNTHESIS AND BROMINATION OF 1-ALLYL-3-(ARYLAMINOMETHYLENE)QUINOLINE-2,4-(1H,3H)-DIONES

被引：10

作者：

Ukrainets, I. V. ^{[1
]}

Liu Yangyang ^{[1
]}

Bereznyakova, N. L. ^{[1
]}

Turov, A. V. ^{[2
]}

机构：

[1] Natl Univ Pharm, UA-61002 Kharkov, Ukraine

[2] Taras Shevchenko Natl Univ, UA-01033 Kiev, Ukraine

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2009年 / 45卷 / 10期

关键词：

1-allyl-3-(arylaminomethylene)quinoline-2,4-(1H,3H)-diones; 1-allyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbaldehyde; enamines; oxazolo[3,2-a]quinolines; Schiff bases; bromination; halocyclization;

D O I：

10.1007/s10593-010-0412-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bromination of 1-allyl-substituted 3-(arylaminomethylene)quinoline-2,4-(1H,3H)-diones with one equivalent of molecular bromine in glacial acetic acid and subsequent dilution of the reaction mixture with water is accompanied by halocyclization and hydrolysis to form 2-bromomethyl-5-oxo-1,2 dihydro-5H- oxazolo[3,2-a]quinoline-4-carbaldehyde.

引用

页码：1235 / 1240

页数：6

共 11 条

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[9] 4-Hydroxy-2-quinolones 129. Synthesis and structure of 2-bromomethyl-4- carboxy-5-methyl-1,2-dihydrooxazolo-[3,2-a]quinolinium bromide
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