SYNTHESIS OF SOME NEW NITROGEN BRIDGE-HEAD PYRIDO[1,2,4]TRIAZEPINES

被引：16
|
作者：
Abdel-Megid, M. [1 ]
机构：
[1] Ain Shams Univ, Fac Educ, Dept Chem, Cairo, Egypt
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2009年 / 45卷 / 12期
关键词：
pyridotriazepines; pyridotriazines; triazolopyridines; POLYFUNCTIONALLY SUBSTITUTED HETEROAROMATICS; 1,3-DIPOLAR CYCLOADDITION; DERIVATIVES; ROUTE; AGENTS;
D O I：
10.1007/s10593-010-0460-y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Ring closure reactions of 1,6-diamino-4-(4-chlorophenyl)-2-oxopyridine-3,5-dicarbonitrile with various 1,3-dielectrophiles, namely, diethyl malonate, ethyl ethoxymethylenecyanoacetate, 2-cyano3,3- bis(methylthio) acrylonitrile, dimethyl acetylenedicarboxylate, dehydroacetic acid, chromone3- carbonitrile, and 3-formylchromone led to the formation of the target biheterocyclic 1,2,4-triazepines. The reactions with 3-phenylazo-2,4-pentadione, ethyl alpha-cyano-a-phenylazoacetate, and 3,1-benzoxazin- 4-one derivative are also described.
引用
收藏
页码：1523 / 1531
页数：9
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