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The ldb1 mutant of Saccharomyces cerevisiae is defective in Pmr1p, the yeast secretory pathway/Golgi Ca2+/Mn2+-ATPase
被引:9
|作者:
Olivero, I
[1
]
Corbacho, I
[1
]
Hernández, LM
[1
]
机构:
[1] Univ Extremadura, Dept Microbiol, E-06071 Badajoz, Spain
关键词:
Saccharomyces cerevisiae;
glycosylation;
phosphorylation;
golgi apparatus;
LDB1;
PMR1;
D O I:
10.1016/S0378-1097(03)00002-8
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The LDB1 gene of Saccharomyces cerevisiae was identified by complementation of the ldb1 mutant phenotype with a genomic library. We found that the ldb1 defect is complemented by PMR1 which codes for the yeast secretory pathway/Golgi Ca2+/Mn2+-ATPase. Besides that, the analysis of a null mutation of the PMR1 gene revealed a phenotype identical to that of ldb1 mutant. Thus, LDB1 must be considered a synonym of PMR1. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
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页码:137 / 142
页数:6
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