The LDB1 gene of Saccharomyces cerevisiae was identified by complementation of the ldb1 mutant phenotype with a genomic library. We found that the ldb1 defect is complemented by PMR1 which codes for the yeast secretory pathway/Golgi Ca2+/Mn2+-ATPase. Besides that, the analysis of a null mutation of the PMR1 gene revealed a phenotype identical to that of ldb1 mutant. Thus, LDB1 must be considered a synonym of PMR1. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
机构:
Mahidol Univ, Siriraj Hosp, Dept Microbiol, Fac Med, Bangkok 10700, ThailandDuke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Pinchai, Nadthanan
Juvvadi, Praveen Rao
论文数: 0引用数: 0
h-index: 0
机构:Duke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Juvvadi, Praveen Rao
Fortwendel, Jarrod R.
论文数: 0引用数: 0
h-index: 0
机构:
Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USADuke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Fortwendel, Jarrod R.
Perfect, B. Zachary
论文数: 0引用数: 0
h-index: 0
机构:Duke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Perfect, B. Zachary
Rogg, Luise E.
论文数: 0引用数: 0
h-index: 0
机构:Duke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Rogg, Luise E.
Asfaw, Yohannes G.
论文数: 0引用数: 0
h-index: 0
机构:
Duke Univ, Med Ctr, Dept Lab Anim Resources, Durham, NC 27710 USADuke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Asfaw, Yohannes G.
Steinbach, William J.
论文数: 0引用数: 0
h-index: 0
机构:
Duke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA
Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USADuke Univ, Med Ctr, Div Pediat Infect Dis, Dept Pediat, Durham, NC 27710 USA