Retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from Maryland

被引:16
作者
Bunnell, JE
Dumler, JS
Childs, JE
Glass, GE
机构
[1] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA
[2] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21205 USA
[3] Ctr Dis Control & Prevent, Natl Ctr Infect Dis, Viral & Rickettsial Zoonoses Branch, Atlanta, GA 30333 USA
关键词
Ehrlichia equi; human granulocytic ehrlichiosis; indirect immunofluorescence assay; Peromyscus leucopus; reservoir; white-footed mouse;
D O I
10.7589/0090-3558-34.1.179
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Archived serum samples from 111 Peromyscus leucopus, collected 1984-88 in Baltimore City (Maryland, USA), were analyzed by indirect immunofluorescence assay. Sera from two (2%) individuals contained antibodies reactive to Ehrlichia equi and the human granulocytic ehrlichiosis (HGE) agent. This suggests that the HGE agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case of human disease was recognized.
引用
收藏
页码:179 / 181
页数:3
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