Perimembranous ventricular septal defect closure in infants with KONAR-MF occluder

Background: Ventricular septal defect (VSD) with significant left to right shunt requires closure. Device closure in Infants with perimembranous VSD and moderate left to right shunt is emerging as an indication in selective cases. Objective: Analysis of infants with moderate perimembranous VSD closed with new KONAR MF occluder. Methods: Infants with perimembranous VSD and moderate left to right shunt who underwent device closure with KONAR MF device (Lifetech Inc., Shenzhen, China) in a tertiary care setup were analyzed retrospectively. Results: Five infants had perimembranous VSD with moderate left to right shunt. They underwent device closure with a KONAF MF device. The mean age was 7.8 months and the mean defect size was 4.3 mm. The VSD was crossed antegradely in two patients and retrogradely in three patients. All but one patient had an antegrade deployment. The KONAR MF device size ranged from 6-4 mm to 10-8 mm. The device was deployed with either Launcher guiding catheter (Medtronic AVE, Santa Rosa, CA) 5F and 6F or 5F Lifetech delivery system. Successful deployment was possible in all patients. One patient had tilting of the device 3 h after the procedure with significant residual flow. The patient was sent for surgery after combined cardiology and surgical discussion. All other infants had stable device positions. There was no residual flow and no significant aortic regurgitation or any hemolysis. In the mean follow up of 15 months, they were all doing well, had good device performance with no evidence of heart block. Conclusions: Device closure of moderate sized perimembranous VSD in infants with KONAR MF occluder appeared to be safe and effective in short term follow up. Larger studies with long term data will help with future recommendations.