Polymer sieving matrices in microanalytical electrophoresis

被引：34
作者：
Chung, Minsub [1 ]
Kim, Dohyun [2 ]
Herr, Amy E. [3 ,4 ,5 ]
机构：
[1] Hongik Univ, Dept Chem Engn, Seoul 121791, South Korea
[2] Myongji Univ, Dept Mech Engn, Yongin 449728, South Korea
[3] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94706 USA
[4] Univ Calif Berkeley, Grad Program Bioengn, Berkeley, CA 94706 USA
[5] Univ Calif San Francisco, Grad Program Bioengn, San Francisco, CA 94706 USA
来源：
ANALYST | 2014年 / 139卷 / 22期
关键词：
SODIUM DODECYL-SULFATE; CAPILLARY GEL-ELECTROPHORESIS; INDUCED FLUORESCENCE DETECTION; LASER-INDUCED FLUORESCENCE; STRANDED-DNA FRAGMENTS; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; POLY(METHYL METHACRYLATE) MICROCHIPS; PERFORMANCE LIQUID-CHROMATOGRAPHY; QUASI-INTERPENETRATING NETWORK; CROSS-LINKED POLYACRYLAMIDE;
D O I：
10.1039/c4an01179a
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Microfluidic design has advanced existing protein separation capabilities and supported novel assays: Key metrics for successful protein separations include fast, robust, and sensitive analysis of complex mixtures of bio-macromolecules. Attaining high separation resolution is a chief concern. Here we review recent advances in polymer-based electrophoresis sieving materials that are impacting microfluidic bioanalytical applications. Looking forward, we comment on unmet needs for advanced separation media in micro-to-nanoscale devices.
引用
收藏
页码：5635 / 5654
页数：20
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