Retinal Vasculitis in a Patient With Mixed Connective Tissue Disease Following COVID-19 Infection: Correlation or Coincidence?

被引:1
作者
Mehta, Salil [1 ]
Gill, Niharika [2 ]
机构
[1] Lilavati Hosp, Ophthalmol, Mumbai, Maharashtra, India
[2] Lilavati Hosp, Rheumatol, Mumbai, Maharashtra, India
关键词
systemic inflammatory and autoimmune disease; fundoscopy; covid-19; retinal vasculitis; mixed connective tissue disease;
D O I
10.7759/cureus.26365
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report the systemic and ophthalmic findings in a female patient with mixed connective tissue disease (MCTD) who subsequently developed retinal vasculitis following coronavirus disease 2019 (COVID-19) reinfection. The patient was a known case of MCTD maintained in remission on immunosuppressive treatment. She subsequently developed retinal vasculitis with areas of capillary non-perfusion in the right eye. This was a finding not seen previously. She was started on an enhanced immunosuppressive regimen along with scatter laser photocoagulation. COVID-19 has been reported to lead to the development of autoimmune disease, both de novo as well as the worsening of pre-existing disease. The onset of retinal vasculitis may potentially be due to a post-COVID-19 exacerbation of her Fe-existing MCTD. Physicians should be aware of this possibility and screen for the same.
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相关论文
共 13 条
[1]   PLASMAPHERESIS TREATMENT OF CENTRAL RETINAL VEIN OCCLUSION IN A YOUNG-ADULT [J].
DODDS, EM ;
LOWDER, CY ;
FOSTER, RE .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1995, 119 (04) :519-521
[2]  
Felipe Flores-Suarez L, 2000, Curr Rheumatol Rep, V2, P396
[3]   Case Report: Systemic Sclerosis After Covid-19 Infection [J].
Fineschi, Serena .
FRONTIERS IN IMMUNOLOGY, 2021, 12
[4]   Immunopathology of Hyperinflammation in COVID-19 [J].
Gustine, Joshua N. ;
Jones, Dennis .
AMERICAN JOURNAL OF PATHOLOGY, 2021, 191 (01) :4-17
[5]   Complications of COVID-19 Pneumonia and Multiple Sclerosis Exacerbation [J].
Jaisankar, Prashanth J. ;
Kucera, Aurelia ;
Lomiguen, Christine M. ;
Chin, Justin .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (08)
[6]   New-onset lupus nephritis associated with COVID-19 infection [J].
Kazzi, Brigitte ;
Fine, Derek ;
Geetha, Duvuru ;
Chung, Melody ;
Monroy-Trujillo, Manny ;
Timlin, Homa .
LUPUS, 2022, 31 (08) :1007-1011
[7]   Retinal Vasculopathy Associated with Mixed Connective Tissue Disease [J].
Kim, Yong-Kyu ;
Woo, Se Joon ;
Lee, Yun Jong ;
Park, Kyu Hyung .
OCULAR IMMUNOLOGY AND INFLAMMATION, 2010, 18 (01) :13-15
[8]  
Margolis Ron, 2007, Semin Ophthalmol, V22, P105, DOI 10.1080/08820530701420074
[9]   Retinal vasculitis and vitreous hemorrhage associated with mixed connective tissue disease [J].
Mimura T. ;
Usui T. ;
Amano S. ;
Yamagami S. ;
Ono K. ;
Noma H. ;
Funatsu H. .
International Ophthalmology, 2005, 26 (4-5) :159-161
[10]   Mixed connective tissue disease: An overview of clinical manifestations, diagnosis and treatment [J].
Ortega-Hernandez, Oscar-Danilo ;
Shoenfeld, Yehuda .
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2012, 26 (01) :61-72