Prevalence of multimorbidity and its association with outcomes in older emergency general surgical patients: an observational study

被引:58
作者
Hewitt, Jonathan [1 ]
McCormack, Caroline [2 ]
Tay, Hui Sian [2 ]
Greig, Matthew [2 ]
Law, Jennifer [3 ]
Tay, Adam [4 ]
Asnan, Nurwasimah Hj [4 ]
Carter, Ben [1 ]
Myint, Phyo Kyaw [2 ,5 ]
Pearce, Lyndsay [3 ]
Moug, Susan J. [4 ]
McCarthy, Kathryn [6 ]
Stechman, Michael J. [7 ]
机构
[1] Cardiff Univ, Div Populat Med, Cardiff CF10 3AX, S Glam, Wales
[2] Aberdeen Royal Infirm, Dept Med Elderly, Aberdeen, Scotland
[3] Manchester Royal Infirm, Dept Gen Surg, Oxford Rd, Manchester M13 9WL, Lancs, England
[4] Royal Alexandra Hosp, Dept Gen Surg, Paisley, Renfrew, Scotland
[5] Univ Aberdeen, Sch Med & Dent, Inst Appl Hlth Sci, Epidemiol Grp, Aberdeen, Scotland
[6] North Bristol NHS Trust, Dept Gen Surg, Bristol, Avon, England
[7] Univ Wales Hosp, Dept Gen Surg, Cardiff CF4 4XW, S Glam, Wales
关键词
GERIATRIC MEDICINE; EPIDEMIOLOGY; SURGERY; Multimorbidity; POSTOPERATIVE COMPLICATIONS; HEALTH-CARE; FRAILTY; ADULTS; INDEXES;
D O I
10.1136/bmjopen-2015-010126
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives Multimorbidity is the presence of 2 or more medical conditions. This increasingly used assessment has not been assessed in a surgical population. The objectives of this study were to assess the prevalence of multimorbidity and its association with common outcome measures. Design A cross-sectional observational study. Setting A UK-based multicentre study, included participants between July and October 2014. Participants Consecutive emergency (non-elective) general surgical patients admitted to hospital, aged over 65years. Outcome measures The outcome measures were (1) the prevalence of multimorbidity and (2) the association between multimorbidity and frailty; the rate and severity of surgery; length of hospital stay; readmission to hospital within 30days of discharge; and death at 30 and 90days. Results Data were collected on 413 participants aged 65-98years (median 77years, (IQR (70-84)). 51.6% (212/413) participants were women. Multimorbidity was present in 74% (95% CI 69.7% to 78.2%) of the population and increased with age (p<0.0001). Multimorbidity was associated with increasing frailty (p for trend <0.0001). People with multimorbidity underwent surgery as often as those without multimorbidity, including major surgery (p=0.03). When comparing multimorbid people with those without multimorbidity, we found no association between length of hospital stay (median 5days, IQR (1-54), vs 6days (1-47), (p=0.66)), readmission to hospital (64 (21.1%) vs 18 (16.8%) (p=0.35)), death at 30days (14 (4.6%) vs 6 (5.6%) (p=0.68)) or 90-day mortality (28 (9.2%) vs 8 (7.6%) (p=0.60)). Conclusions and implications Multimorbidity is common. Nearly three-quarters of this older emergency general surgical population had 2 or more chronic medical conditions. It was strongly associated with age and frailty, and was not a barrier to surgical intervention. Multimorbidity showed no associations across a range of outcome measures, as it is currently defined. Multimorbidity should not be relied on as a useful clinical tool in guidelines or policies for older emergency surgical patients.
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