Enantioselective epoxidation of α,β-unsaturated ketones by phase-transfer catalysis using chiral quaternary ammonium salts

被引：46
作者：
Kim, DY
Choi, YJ
Park, HY
Joung, CU
Koh, KO
Mang, JY
Jung, KY
机构：
[1] Soonchunhyang Univ, Dept Chem, Chungnam 336600, South Korea
[2] Kangnung Natl Univ, Dept Ind Chem, Kangnung, South Korea
来源：
SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 03期
关键词：
chiral ammonium salt; enantioselective epoxidation; phase-transfer catalysis; alpha; beta-unsaturated ketones;
D O I：
10.1081/SCC-120015774
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The catalytic enantio selective epoxidation promoted by quaternary ammonium salt as a phase transfer catalyst is described. Treatment chalcone derivatives with sodium hypochlorite under mild reaction conditions afforded the corresponding epoxy ketones in good yields with good to moderate enantiomeric excesses.
引用
收藏
页码：435 / 443
页数：9
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