Efficacy and Safety of Mechanical Thrombectomy in Treating Acute Ischemic Stroke: A Meta Analysis

被引：2

作者：

Liu, Yao ^{[2
]}

Zhang, Lin ^{[1
]}

Hong, Peiwei ^{[1
]}

机构：

[1] Sichuan Univ, West China Hosp, Dept Neurol, 17th,Sect 3,Renmin Southern Rd, Chengdu 610041, Sichuan Provinc, Peoples R China

[2] Xindu Hosp Tradit Chinese Med, Chengdu, Sichuan Provinc, Peoples R China

来源：

JOURNAL OF INVESTIGATIVE SURGERY | 2016年 / 29卷 / 02期

关键词：

acute ischemic stroke; meta analysis; IV rtPA; thrombolysis; endovascular treatment; mechanical thrombectomy; INTRAVENOUS T-PA; ENDOVASCULAR TREATMENT; INTERVENTIONAL MANAGEMENT; RANDOMIZED-TRIAL; III TRIAL; IMAGING SELECTION; ARTERY OCCLUSIONS; THERAPY; SOLITAIRE; DEVICE;

D O I：

10.3109/08941939.2015.1067738

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Objectives: Mechanical thrombectomy (MT) is a promising treatment for acute ischemic stroke (AIS). But the results of completed trials were contradictory. Hence, we performed a meta-analysis to evaluate the efficacy and safety of MT in treating AIS. Methods: Literatures were searched in the databases including Pubmed, Cochrane Library, Web of Science and Ovid-SP. The bias and quality of publications with randomized controlled trials (RCTs) were assessed with the Cochrane collaboration's tool for assessing risk of bias. Results: Totally 16 publications matched the inclusion criteria, including seven independent RCTs and 2043 AIS patients. The results showed that the recanalization rate and the modified Rankin score of 0-2 at 90days after treatment were better in MT combining standard care group, but the mortality had no significant difference, even the incidence of intracerebral hemorrhage during follow-up period was worse, as compared with standard care group. Conclusion: MT combining standard care would be an effective and promising treatment for AIS patients according to the present study.

引用

页码：106 / 111

页数：6

共 38 条

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