IRE1: A role in upregulation of ER degradation

被引：16

作者：

Hampton, RY ^{[1
]}

机构：

[1] Univ Calif San Diego, Sect Cell & Dev Biol, Div Biol Sci, San Diego, CA 92103 USA

来源：

DEVELOPMENTAL CELL | 2003年 / 4卷 / 02期

关键词：

D O I：

10.1016/S1534-5807(03)00032-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The unfolded protein response entered the mechanistic realm with the discovery of IRE1 as the key signal transducer in yeast. Although also found in mammals, it appeared to function in assisting the work of other players. The featured studies indicate a separate role for IRE1, and highlight the flexibility that bigger eukaryotes possess in this critical pathway.

引用

页码：144 / 146

页数：3

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