Hydroxyapatite supported copper catalyst for effective three-component coupling

被引：149

作者：

Choudary, BM ^{[1
]}

Sridhar, C ^{[1
]}

Kantam, ML ^{[1
]}

Sreedhar, B ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 39期

关键词：

D O I：

10.1016/j.tetlet.2004.08.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling of three-components, namely an aldehyde, an alkyne and an amine to prepare propargylamines was performed using copper exchanged hydroxyapatite (CuHAP) as the catalyst under mild reaction conditions and in the absence of any co-catalyst. A variety of aldehydes and amines were converted to the corresponding propargylamines, demonstrating the versatility of the reaction. CuHAP was recovered quantitatively by simple filtration and reused several times. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：7319 / 7321

页数：3

共 27 条

[1]

Blomberg C., 1993, The Barbier reaction and related one-step processes

[2] REACTIVITY OF ALLYLIC ORGANOMETALLIC COMPOUNDS OF LITHIUM, SODIUM, MAGNESIUM, ZINC, CADMIUM AND ALUMINUM - RECENT ADVANCES [J].

COURTOIS, G ;

MIGINIAC, L .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1974, 69 (01) :1-44

[3] CHAIN-EXTENSION OF CARBOHYDRATES .4. A STEREOCONTROLLED SYNTHESIS OF A LINCOSAMINE PRECURSOR [J].

CZERNECKI, S ;

VALERY, JM .

JOURNAL OF CARBOHYDRATE CHEMISTRY, 1990, 9 (05) :767-770

[4]

Elliott J.C., 1994, STRUCT CHEM APATITES, V18, P111

[5] Direct addition of TMS-acetylene to aldimines catalyzed by a simple, commercially available Ir(I) complex [J].

Fischer, C ;

Carreira, EM .

ORGANIC LETTERS, 2001, 3 (26) :4319-4321

[6] COPPER(I)-CATALYZED AMINATION OF PROPARGYL ESTERS - SELECTIVE SYNTHESIS OF PROPARGYLAMINES, 1-ALKEN-3-YLAMINES, AND (Z)-ALLYLAMINES [J].

IMADA, Y ;

YUASA, M ;

NAKAMURA, I ;

MURAHASHI, S .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (09) :2282-2284

[7]

IOFFE ST, 1976, ORGANIC COMPOUNDS MA

[8]

KOPKA IE, 1980, J ORG CHEM, V45, P4612

[9]

Koradin C, 2002, ANGEW CHEM INT EDIT, V41, P2535, DOI 10.1002/1521-3773(20020715)41:14<2535::AID-ANIE2535>3.0.CO

[10]

2-M

← 1 2 3 →