Role of the intestinal MALT in pathogenesis of the IgA-nephropathy

被引：0
作者：
Guliaev, Sergei, V [1 ]
Strizhakov, Leonid A. [1 ,2 ]
Chebotareva, Natalia, V [1 ,2 ]
Moiseev, Sergei, V [1 ,2 ]
机构：
[1] Sechenov Univ, Sechenov Moscow State Med Univ 1, Moscow, Russia
[2] Lomonosov Moscow State Univ, Moscow, Russia
来源：
TERAPEVTICHESKII ARKHIV | 2021年 / 93卷 / 06期
关键词：
immunoglobulin A-nephropathy; immunoglobulin A; aberrant glycosylation of immunoglobulin A; intestinal permeability; MALT; IMMUNE-COMPLEXES; GLYCOSYLATED IGA1; LIVER-DISEASE; PERMEABILITY; PURPURA; ANTIBODIES; EDTA; ENDOTOXEMIA; CHILDREN; ANTIGENS;
D O I：
10.26442/00403660.2021.06.200868
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or abnormal intestinal permeability are discussed in details. Based on supposed entero-renal pathogenesis of the disease future treatment modalities are considered. Relevant world's literature is cited.
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收藏
页码：724 / 728
页数：5
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